Introduction

Nintedanib 150 mg, marketed under the brand name NINTEDONE 150 by Steris Healthcare Pvt Ltd, is a prescription medicine primarily used for the treatment of Idiopathic Pulmonary Fibrosis (IPF), Interstitial Lung Diseases (ILDs) with a progressive phenotype, and Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD). It belongs to a class of medicines known as tyrosine kinase inhibitors (TKIs) that help slow down lung fibrosis (scarring) and maintain lung function. Patients with chronic lung diseases often rely on Nintedanib to reduce disease progression and improve quality of life. At Steris Healthcare Pvt Ltd, we manufacture NINTEDONE 150 (Nintedanib 150 mg Soft Gelatin Capsules) under WHO-GMP-certified facilities, ensuring safety, affordability, and global quality standards.

Composition

• Active Ingredient: Nintedanib 150 mg

• Brand Name: NINTEDONE 150

• Dosage Form: Soft Gelatin Capsule

• Manufacturer: Steris Healthcare Pvt Ltd

What is Nintedanib 150 mg Used For?

Nintedanib 150 mg has multiple therapeutic uses:

1. Idiopathic Pulmonary Fibrosis (IPF) – A rare, progressive lung disease that leads to scarring of the lungs, causing breathing difficulties.

2. Chronic Fibrosing Interstitial Lung Diseases (ILDs) – Helps in slowing the progression of fibrosis in various ILDs.

3. Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD) – Prevents lung scarring caused by systemic sclerosis (scleroderma).

4. Other Progressive Pulmonary Fibrosis Conditions – Improves lung function and slows decline in chronic lung fibrosis.

Nintedanib Mechanism of Action

Nintedanib works by blocking multiple pathways that promote fibrosis and abnormal blood vessel growth:

• Inhibits Growth Factor Receptors: VEGFR (Vascular Endothelial Growth Factor Receptor), PDGFR (Platelet-Derived Growth Factor Receptor), and FGFR (Fibroblast Growth Factor Receptor).

• Reduces Fibroblast Activity: Slows down scarring (fibrosis) of lung tissue.

• Preserves Lung Function: Helps patients maintain breathing capacity for a longer time.

This makes NINTEDONE 150 a key drug in modern pulmonary care.

Benefits of Nintedanib 150 mg (NINTEDONE 150)

• Slows down the progression of lung fibrosis.

• Reduces the rate of lung function decline.

• Provides a better quality of life for patients with IPF and ILDs.

• It can be used long-term under medical supervision.

• Available in easy-to-swallow soft gelatin capsules.

Dosage & Administration

• Recommended Dose: 150 mg twice daily (every 12 hours), or as prescribed by the doctor.

• Route: Oral – swallowed whole with water.

• With Food: Taking capsules with food reduces gastrointestinal side effects.

• Treatment Duration: Long-term therapy depending on disease progression and patient response.

Note: Dose adjustment may be needed for patients with liver problems or side effects.

Nintedanib 150 mg Side Effects

Common Side Effects

• Diarrhea (very common)

• Nausea or vomiting

• Abdominal pain

• Loss of appetite

• Weight loss

• Tiredness or weakness

Serious Side Effects (Consult a Doctor Immediately)

• Liver function problems (elevated enzymes, jaundice)

• Increased bleeding risk (especially if on blood thinners)

• High blood pressure

• Gastrointestinal perforation (rare but serious)

Regular liver function tests, blood pressure checks, and medical monitoring are essential.

Precautions & Warnings

• Not safe for pregnant or breastfeeding women.

• Use with caution in patients with liver disease or heart problems.

• Avoid alcohol during treatment.

• Do not chew or crush the capsule.

• Always follow the doctor’s prescription strictly.

Drug Interactions

Nintedanib may interact with:

• Anticoagulants (Warfarin, Heparin) → may increase bleeding risk.

• CYP3A4 modulators (Ketoconazole, Rifampicin) → can alter drug levels.

• Other antifibrotic medications → require close monitoring.

Storage Instructions

• Store at 15–25°C in a dry place.

• Protect from direct sunlight and moisture.

• Keep away from children.

Nintedanib 150 mg Price in India

The nintedanib 150 mg price in India varies depending on brand and location. Steris Healthcare Pvt Ltd ensures NINTEDONE 150 is available at a competitive and affordable price without compromising on quality.

Why Buy NINTEDONE 150 from Steris Healthcare Pvt Ltd?

Steris Healthcare Pvt Ltd is a trusted name in pharmaceuticals, known for quality, innovation, and affordability.

•  WHO-GMP Certified Manufacturing

•  Wide Range of Pharmaceutical Products

•  Affordable Pricing Without Compromising Quality

•  Pan-India Supply Network

•  Trusted by Doctors & Patients

By choosing NINTEDONE 150 from Steris Healthcare, patients receive safe, effective, and reliable treatment for chronic lung diseases.

Frequently Asked Questions (FAQs)

Q1: What is Nintedanib 150 mg used for?
A: It is used for idiopathic pulmonary fibrosis (IPF), interstitial lung diseases (ILDs), and systemic sclerosis-associated ILD.

Q2: How does Nintedanib 150 mg work?
A: It blocks VEGFR, PDGFR, and FGFR pathways, slowing lung fibrosis progression.

Q3: What are the common side effects of Nintedanib 150 mg?
A: Diarrhea, nausea, abdominal pain, loss of appetite, and fatigue.

Q4: Can I take Nintedanib 150 mg with food?
A: Yes, it should be taken with food to reduce stomach-related side effects.

Q5: Is Nintedanib 150 mg affordable?
A: Yes, Steris Healthcare provides NINTEDONE 150 at an affordable cost with global quality assurance.

Conclusion

NINTEDONE 150 (Nintedanib 150 mg Soft Gelatin Capsules) is a trusted and effective treatment for idiopathic pulmonary fibrosis, interstitial lung diseases, and systemic sclerosis-associated lung fibrosis. It helps slow disease progression, preserve lung function, and improve the overall quality of life. At Steris Healthcare Pvt Ltd, we are dedicated to providing safe, effective, and affordable medicines. By choosing NINTEDONE 150, patients can access quality treatment with the trust and reliability of Steris Healthcare.