Introduction

Nintedanib 100 mg, available under the brand name NINTEDONE 100 by Steris Healthcare Pvt Ltd, is an advanced medication used for the treatment of idiopathic pulmonary fibrosis (IPF), chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype, and systemic sclerosis-associated interstitial lung disease (SSc-ILD). It belongs to the class of tyrosine kinase inhibitors (TKIs) and works by slowing down the progression of lung fibrosis, improving breathing function, and enhancing the quality of life in patients with chronic lung conditions. At Steris Healthcare Pvt Ltd, we ensure that NINTEDONE 100 (Nintedanib 100 mg Soft Gelatin Capsules) is manufactured under WHO-GMP-certified facilities, guaranteeing safety, efficacy, and affordability.

Composition

• Active Ingredient: Nintedanib 100 mg

• Brand Name: NINTEDONE 100

• Dosage Form: Soft Gelatin Capsule

• Manufacturer: Steris Healthcare Pvt Ltd

What is Nintedanib 100 mg Used For?

Nintedanib 100 mg is prescribed for:

1. Idiopathic Pulmonary Fibrosis (IPF) – A chronic, progressive lung disease that causes scarring of lung tissue and breathing difficulties.

2. Interstitial Lung Diseases (ILDs) – Helps in slowing disease progression in various fibrosing lung conditions with a progressive phenotype.

3. Systemic Sclerosis-Associated ILD (SSc-ILD) – Prevents lung fibrosis caused by systemic sclerosis (scleroderma).

4. Chronic Progressive Lung Fibrosis – Reduces worsening of lung function and improves long-term survival.

Nintedanib Mechanism of Action

Nintedanib is a triple angiokinase inhibitor that blocks multiple signaling pathways involved in fibrosis and angiogenesis:

• Inhibits Receptors: Vascular Endothelial Growth Factor Receptor (VEGFR), Platelet-Derived Growth Factor Receptor (PDGFR), and Fibroblast Growth Factor Receptor (FGFR).

• Prevents Fibrosis Progression: Reduces fibroblast activity, slowing lung scarring.

• Improves Lung Function: Helps maintain breathing capacity for longer periods.

Benefits of Nintedanib 100 mg (NINTEDONE 100)

• Slows down disease progression in IPF and ILDs.

• Reduces the risk of lung function decline.

• Provides a better quality of life for patients with chronic lung diseases.

• It can be used in combination with other supportive therapies.

• Available in easy-to-swallow soft gelatin capsules.

Dosage & Administration

• Recommended Dose: 100 mg to 150 mg twice daily (as prescribed by the physician).

• Route: Oral, swallowed whole with water.

• With Food: Taking with food reduces gastrointestinal side effects.

• Treatment Duration: Long-term therapy depending on disease progression.

Note: Dose adjustment may be required in patients with liver impairment.

Nintedanib 100 mg Side Effects

Like all medicines, NINTEDONE 100 may cause some side effects:

Common Side Effects

• Diarrhea (most common)

• Nausea or vomiting

• Abdominal pain

• Loss of appetite and weight loss

• Fatigue or weakness

• Headache

Serious Side Effects (Consult a Doctor Immediately)

• Liver enzyme elevation (hepatotoxicity)

• Bleeding risk

• High blood pressure

• Gastrointestinal perforation (rare but serious)

Regular liver function tests and blood pressure monitoring are recommended during treatment.

Precautions & Warnings

• Not recommended for pregnant or breastfeeding women.

• Caution in patients with liver disease, heart conditions, or bleeding risk.

• Avoid alcohol during treatment.

• Do not crush or chew the capsule.

• Regular medical monitoring is essential.

Drug Interactions

Nintedanib may interact with:

• Anticoagulants (warfarin, heparin) → increased bleeding risk.

• Strong CYP3A4 inhibitors/inducers → may affect drug levels.

• Other antifibrotic medications → combined therapy must be supervised.

Storage Instructions

• Store at room temperature (15–25°C).

• Keep away from direct sunlight and moisture.

• Keep out of reach of children.

Nintedanib 100 mg Price in India

The Nintedanib 100 mg cost in India may vary based on brand and location. Steris Healthcare Pvt Ltd ensures NINTEDONE 100 is available at a competitive and affordable price without compromising on quality.

Why Buy NINTEDONE 100 from Steris Healthcare Pvt Ltd?

Steris Healthcare Pvt Ltd is a trusted pharmaceutical company in India, offering a wide range of quality, affordable medicines.

•  WHO-GMP Certified Manufacturing

•  Global Quality Standards

•  Affordable & Patient-Centric Pricing

•  Wide Distribution Network Across India

•  Ethical Business Practices

By choosing NINTEDONE 100 from Steris Healthcare, patients receive safe, effective, and reliable treatment for chronic lung conditions.

Frequently Asked Questions (FAQs)

Q1: What is Nintedanib 100 mg used for?
A: It is used to treat idiopathic pulmonary fibrosis (IPF), chronic fibrosing ILDs, and systemic sclerosis-associated ILD.

Q2: How does Nintedanib work?
A: It blocks multiple receptors (VEGFR, PDGFR, FGFR) that promote fibrosis, thereby slowing lung scarring.

Q3: What are the common side effects of Nintedanib 100 mg?
A: Diarrhea, nausea, abdominal pain, fatigue, and weight loss are common.

Q4: Can Nintedanib 100 mg be taken with food?
A: Yes, it should be taken with food to minimize gastrointestinal side effects.

Q5: Is Nintedanib 100 mg expensive?
A: The price varies by brand, but Steris Healthcare provides NINTEDONE 100 at an affordable cost with assured quality.

Conclusion

NINTEDONE 100 (Nintedanib 100 mg Soft Gelatin Capsules) is a vital medication in the management of idiopathic pulmonary fibrosis, interstitial lung diseases, and systemic sclerosis-associated lung fibrosis. It helps slow disease progression, preserve lung function, and improve patients’ quality of life. At Steris Healthcare Pvt Ltd, we are committed to providing safe, effective, and affordable medications. Choosing NINTEDONE 100 means choosing trust, quality, and better healthcare outcomes.