Introduction

What is NAPROXZEN D 250?

NAPROXZEN D 250 is a combination medication that includes Naproxen (250mg) and Domperidone SR (30mg). This combination is designed to treat various conditions, particularly those related to pain and inflammation, while also addressing symptoms like nausea that may accompany pain-relief treatments.

• Naproxen (250mg): Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, reduce inflammation, and lower fever. It is commonly used to treat conditions like arthritis, muscle pain, menstrual cramps, and other inflammatory disorders.

• Domperidone SR (30mg): Domperidone is a medication that works as a prokinetic agent, which means it helps increase motility in the digestive system. It is often used to treat nausea and vomiting associated with certain medications, including NSAIDs like Naproxen, which can sometimes cause gastrointestinal irritation.

The SR in Domperidone SR indicates that it is in a sustained-release form, providing a gradual release of the drug for extended effects.

Together, these two active ingredients provide pain relief and help minimize the discomfort or side effects associated with Naproxen, particularly those related to the digestive system.

Composition of NAPROXZEN D 250

• Naproxen (250mg): This is the primary ingredient responsible for reducing inflammation, pain, and fever. It belongs to a class of drugs known as NSAIDs, which block the production of prostaglandins—chemicals in the body that promote inflammation, pain, and fever.

• Domperidone SR (30mg): This ingredient helps to counteract nausea and vomiting, which are common side effects of taking NSAIDs like Naproxen. The sustained-release formulation allows for continuous action over time, ensuring that the drug remains effective without frequent dosing.

Key Features of NAPROXZEN D 250

1. Pain Relief:

   • The Naproxen component of NAPROXZEN D 250 is effective in treating various forms of pain, including arthritis, muscle pain, back pain, and menstrual cramps. It reduces inflammation at the site of pain, providing both immediate and long-lasting relief.

2. Anti-inflammatory Action:

   • Naproxen helps to reduce inflammation in conditions such as arthritis, tendonitis, and bursitis. By inhibiting cyclooxygenase (COX) enzymes, it reduces the production of prostaglandins, the chemicals responsible for inflammation and pain.

3. Prevents Gastrointestinal Irritation:

   • One of the most common side effects of NSAIDs is gastrointestinal upset, including nausea and indigestion. Domperidone SR helps prevent and treat nausea, minimizing the stomach discomfort that can occur with pain relievers like Naproxen.

4. Sustained Release:

   • The sustained-release form of Domperidone ensures that the medication works over an extended period, providing relief from nausea throughout the day, especially for those who take NSAIDs regularly.

5. Convenient Dosing:

   • NAPROXZEN D 250 combines two important medications in one tablet, making it easier for patients to manage their pain and any related gastrointestinal issues with a single dose.

How NAPROXZEN D 250 Works

Naproxen (250mg) works by inhibiting the activity of COX enzymes (cyclooxygenase-1 and cyclooxygenase-2), which are involved in the production of prostaglandins. These prostaglandins are the chemicals responsible for causing inflammation, pain, and fever. By reducing their production, Naproxen helps alleviate symptoms of pain and inflammation in conditions like arthritis, muscle injuries, and menstrual cramps.

Domperidone SR (30mg) acts primarily on the gastrointestinal system, where it works to increase the movement of food and waste products through the digestive tract, which can be helpful for patients experiencing nausea or bloating. It specifically targets the dopamine receptors in the gut and helps to speed up gastric emptying, thus reducing nausea and vomiting that may occur with NSAID use.

By combining Naproxen with Domperidone, NAPROXZEN D 250 helps address both the pain and inflammation while also mitigating one of the most common side effects (nausea) associated with NSAIDs.

Usage of NAPROXZEN D 250

NAPROXZEN D 250 is primarily used for the treatment of pain and inflammation associated with conditions such as:

• Osteoarthritis: A condition that causes inflammation in the joints.

• Rheumatoid Arthritis: An autoimmune disorder that leads to inflammation and pain in the joints.

• Musculoskeletal Pain: Pain affecting the muscles and bones, including back pain or sports injuries.

• Menstrual Cramps: Pain associated with menstruation.

• Gout: A type of arthritis caused by the accumulation of uric acid crystals in the joints.

Additionally, the Domperidone SR component makes it particularly useful for individuals who experience nausea or stomach upset when using Naproxen or other NSAIDs.

Dosage:

• Adults: The usual recommended dose is one tablet (250mg Naproxen and 30mg Domperidone SR) taken once or twice daily, depending on the severity of the condition and the doctor's recommendation.

• Children: This medication is not typically recommended for use in children unless specifically prescribed by a healthcare provider.

Instructions for Use:

• Take NAPROXZEN D 250 with food or after meals to reduce the likelihood of gastrointestinal irritation.

• Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.

• Stick to the prescribed dosage and do not exceed the recommended amount.

Benefits of NAPROXZEN D 250

1. Effective Pain and Inflammation Relief:

   • NAPROXZEN D 250 helps manage both acute and chronic pain, particularly related to inflammatory conditions such as arthritis. It provides effective relief from pain, swelling, and discomfort.

2. Minimized Gastrointestinal Discomfort:

   • The inclusion of Domperidone SR reduces the risk of gastrointestinal side effects like nausea, indigestion, and stomach irritation, which are commonly experienced by patients taking NSAIDs like Naproxen.

3. Convenient Combined Therapy:

   • NAPROXZEN D 250 combines two drugs—one for pain relief and one for managing nausea—into a single tablet, improving patient compliance and making it easier to manage both conditions simultaneously.

4. Sustained-Release Formula:

   • The sustained-release formulation of Domperidone provides prolonged relief from nausea, allowing patients to maintain their medication regimen without needing to take additional medications for digestive upset.

5. Non-Steroidal Option:

   • As an NSAID, Naproxen is a non-steroidal option for pain relief, meaning it does not involve the risks associated with corticosteroid treatments, such as immune suppression or osteoporosis.

Side Effects of NAPROXZEN D 250

Like all medications, NAPROXZEN D 250 can cause side effects. While many people tolerate this medication well, some potential side effects include:

• Gastrointestinal Issues: nausea, stomach pain, indigestion, or bloating. However, Domperidone helps minimize these effects.

• Drowsiness or Dizziness: These effects may occur due to the Domperidone component.

• Headaches: Common with both Naproxen and Domperidone use.

• Skin Reactions: Rash or itching may occur in rare cases.

• Kidney Issues: Prolonged use of Naproxen may lead to kidney problems, particularly in patients with pre-existing kidney disease.

• Heart Risks: As with other NSAIDs, prolonged use of Naproxen may increase the risk of heart-related issues, especially in patients with a history of heart disease.

Serious side effects are rare but can include:

• Severe allergic reactions: difficulty breathing, swelling, or anaphylaxis.

• Gastrointestinal bleeding: Long-term use of NSAIDs may lead to ulcers or bleeding in the stomach or intestines.

• Liver problems: Monitor for any signs of liver issues like jaundice, dark urine, or severe fatigue.

If any of these serious side effects occur, it is crucial to seek medical attention immediately.

FAQ Section

1. What is NAPROXZEN D 250 used for?

NAPROXZEN D 250 is used for treating pain and inflammation associated with conditions like arthritis, muscle pain, back pain, and menstrual cramps. It also helps reduce nausea caused by NSAIDs like Naproxen.

2. How does NAPROXZEN D 250 work?

NAPROXZEN D 250 combines Naproxen, which reduces pain and inflammation, with Domperidone, which helps prevent nausea. The combination offers both pain relief and gastrointestinal protection.

3. Can NAPROXZEN D 250 be taken on an empty stomach?

It is best to take NAPROXZEN D 250 with food or after meals to help minimize potential stomach irritation.

4. What are the common side effects of NAPROXZEN D 250?

Common side effects include gastrointestinal issues like nausea, stomach pain, or headaches. The addition of Domperidone helps minimize nausea and vomiting associated with NSAID use.

5. Can I take NAPROXZEN D 250 if I have heart problems?

Patients with a history of heart disease should consult their doctor before using NAPROXZEN D 250, as NSAIDs like Naproxen can increase the risk of heart-related complications.

Conclusion

NAPROXZEN D 250 is a powerful combination of Naproxen (250mg) and Domperidone SR (30mg) that provides effective relief from pain and inflammation while minimizing the gastrointestinal side effects often associated with NSAIDs. This combination medication is ideal for patients who require pain management for conditions like arthritis or muscle pain and are prone to nausea from NSAID use. 

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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