Introduction

What is MESALMILE 800 ER?

MESALMILE 800 ER is an extended-release (ER) formulation of the drug Mesalamine (800mg), primarily used in the management and treatment of inflammatory bowel diseases (IBD), particularly ulcerative colitis. Mesalamine, also known as 5-aminosalicylic acid (5-ASA), is an anti-inflammatory medication that targets the colon to reduce inflammation, alleviate symptoms, and prevent flare-ups associated with IBD. The "ER" in MESALMILE 800 ER indicates that the drug is designed to release the active ingredient over a longer period, ensuring continuous therapeutic action throughout the day with fewer doses required.

Ulcerative colitis and other inflammatory conditions of the gastrointestinal tract can cause pain, diarrhea, rectal bleeding, and abdominal cramping. MESALMILE 800 ER helps reduce these symptoms, providing long-term relief and supporting the maintenance of remission in IBD patients.

Composition of MESALMILE 800 ER

The primary component of MESALMILE 800 ER is Mesalamine (800mg), which is responsible for its therapeutic effects. Mesalamine is a non-steroidal anti-inflammatory drug (NSAID) that specifically acts on the colon, where it reduces inflammation and prevents the recurrence of IBD symptoms.

• Active Ingredient: Mesalamine (800mg)

• Formulation: Extended Release (ER) Tablet

• Excipients: These are inactive ingredients used in the formulation that assist in the controlled-release mechanism of the tablet, ensuring the gradual release of Mesalamine in the gastrointestinal tract.

Key Features of MESALMILE 800 ER

1. Extended Release Formulation:

   • The extended-release technology in MESALMILE 800 ER ensures that Mesalamine is gradually released into the body over time, allowing for consistent levels of the drug to be maintained throughout the day. This feature reduces the need for frequent dosing, improving patient adherence to the treatment plan.

2. Targeted Delivery:

   • Mesalamine is delivered directly to the colon, where it is most needed, to reduce inflammation. This localized action minimizes systemic side effects and enhances the drug’s effectiveness in treating conditions like ulcerative colitis.

3. Improved Symptom Control:

   • MESALMILE 800 ER is designed to alleviate symptoms of IBD, such as abdominal pain, diarrhea, and rectal bleeding, by controlling inflammation and promoting healing of the colon lining.

4. Convenient Dosing Schedule:

   • The 800mg dosage of MESALMILE 800 ER means that patients typically need to take fewer pills, making it easier to follow the prescribed treatment regimen. This is particularly beneficial for patients with chronic conditions that require long-term management.

5. Long-Term Maintenance:

   • MESALMILE 800 ER is not just for acute flare-ups; it also plays a crucial role in maintaining remission, preventing future flare-ups, and improving the quality of life for patients with chronic inflammatory conditions.

How MESALMILE 800 ER Works

Mesalamine, the active ingredient in MESALMILE 800 ER, works by reducing inflammation in the colon, where inflammatory bowel diseases like ulcerative colitis cause the most damage. Here’s how it works:

1. Anti-inflammatory Action:

   • Mesalamine inhibits the activity of cyclooxygenase enzymes (COX) and lipoxygenase enzymes, which are responsible for the production of inflammatory substances called prostaglandins and leukotrienes. By blocking these enzymes, mesalamine helps to reduce inflammation in the colon, which alleviates symptoms such as pain, bleeding, and diarrhea.

2. Localized Effect:

   • The extended-release formulation of MESALMILE 800 ER ensures that the medication is released slowly and directly in the colon, where it’s most needed. This minimizes the systemic absorption of the drug, making the treatment both effective and less likely to cause side effects in other parts of the body.

3. Healing of the Colon Lining:

   • Mesalamine helps promote healing of the inflamed colon lining by reducing the inflammatory response and supporting tissue repair. Over time, this can lead to the maintenance of remission in patients with chronic IBD.

Usage of MESALMILE 800 ER

The dosage of MESALMILE 800 ER is typically determined by the healthcare provider based on the severity of the condition, the patient’s overall health, and their response to treatment.

Dosage and Administration:

• Adults: The standard dosage for adults with ulcerative colitis is typically 800mg, taken one to three times a day, depending on the prescribed regimen. The exact dose and frequency will depend on the specific needs of the patient, and the healthcare provider will adjust the dosage accordingly.

• Children: The use of MESALMILE 800 ER in children should be closely monitored by a pediatric gastroenterologist, as the dosage and safety profile may differ for younger patients.

Instructions for Use:

• Take with a Full Glass of Water: Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet as this could affect the medication’s prolonged-release mechanism.

• Consistency: Try to take MESALMILE 800 ER at the same time each day to maintain steady drug levels and improve treatment adherence.

• Food: The medication can be taken with or without food, but consistent timing is important.

Benefits of MESALMILE 800 ER

1. Reduces Inflammation and Symptoms:

   • MESALMILE 800 ER is effective at reducing the inflammation in the colon that causes the hallmark symptoms of ulcerative colitis, including abdominal pain, diarrhea, rectal bleeding, and cramping.

2. Prevents Flare-Ups:

   • The extended-release formulation of MESALMILE 800 ER helps maintain steady medication levels, preventing future flare-ups of ulcerative colitis and maintaining long-term remission.

3. Improved Patient Adherence:

   • The once or twice-a-day dosing regimen of MESALMILE 800 ER, coupled with the convenient 800mg tablet, makes it easier for patients to adhere to their treatment plan, ensuring better control over their condition.

4. Localized Treatment:

   • MESALMILE 800 ER’s controlled release system ensures that Mesalamine is delivered directly to the colon, where it is needed most, minimizing systemic side effects and maximizing its anti-inflammatory effects.

5. Long-Term Remission and Maintenance:

   • MESALMILE 800 ER is not only useful in treating active flare-ups but is also crucial in maintaining long-term remission, preventing new episodes of IBD, and improving patients' overall quality of life.

Side Effects of MESALMILE 800 ER

Like all medications, MESALMILE 800 ER can cause side effects, though not everyone will experience them. Common side effects include:

• Gastrointestinal Discomfort: nausea, abdominal pain, bloating, or diarrhea.

• Headaches: Some patients may experience headaches while using the medication.

• Rashes or Itching: Some people may develop mild skin reactions like rashes or itching.

Serious but rare side effects can include:

• Kidney Issues: Mesalamine can sometimes affect kidney function, so regular monitoring of kidney function is recommended for long-term users.

• Severe Allergic Reactions: Symptoms may include difficulty breathing, swelling, or anaphylaxis.

• Liver Enzyme Changes: Occasionally, Mesalamine can affect liver function, requiring periodic liver enzyme tests.

If you experience any severe side effects or unusual symptoms, it is important to contact your healthcare provider immediately.

FAQ Section

1. What is MESALMILE 800 ER used for?

MESALMILE 800 ER is used to treat inflammatory bowel diseases, particularly ulcerative colitis. It helps reduce inflammation in the colon, control symptoms such as diarrhea, abdominal pain, and rectal bleeding, and maintain remission.

2. How should I take MESALMILE 800 ER?

Take the tablet whole with a glass of water, without crushing, chewing, or breaking it. Follow the prescribed dosage schedule, and take it at the same time each day for best results.

3. What is the typical dosage of MESALMILE 800 ER?

The typical dose for adults is 800mg once to three times daily, depending on the severity of the condition and the healthcare provider’s instructions.

4. Are there any side effects of MESALMILE 800 ER?

Common side effects include nausea, abdominal pain, diarrhea, and headaches. More serious side effects can include kidney issues and liver enzyme changes. Always contact your healthcare provider if you experience any severe reactions.

5. Can MESALMILE 800 ER be taken during pregnancy or breastfeeding?

Mesalamine should only be used during pregnancy or breastfeeding if the potential benefits outweigh the risks. Consult your healthcare provider before using MESALMILE 800 ER if you are pregnant or breastfeeding.

Conclusion

MESALMILE 800 ER (Mesalamine 800mg) is an essential medication for managing inflammatory bowel diseases, especially ulcerative colitis. The extended-release formulation ensures that the medication is delivered gradually to the colon, providing effective and sustained anti-inflammatory action. By alleviating symptoms, controlling flare-ups, and maintaining remission, MESALMILE 800 ER significantly enhances the quality of life for patients with chronic IBD. 

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

BUY NOW