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Tolperisone 150 mg Tablets: Uses, Dosage, Side Effects, and Benefits

Sep 04, 2025

Introduction

Muscle stiffness, spasms, and spasticity can significantly affect a patient’s mobility and quality of life. TOPERITIME 150 (Tolperisone Hydrochloride Tablets 150 mg) is a centrally acting muscle relaxant that helps reduce abnormal muscle contractions while preserving normal motor function.Unlike many muscle relaxants, Tolperisone does not cause excessive sedation, making it suitable for long-term therapy and daily functioning. It is widely prescribed in conditions such as stroke recovery, multiple sclerosis, spinal cord injuries, post-operative stiffness, and musculoskeletal pain disorders.

Composition

Each film-coated tablet of TOPERITIME 150 contains:

  • Tolperisone Hydrochloride – 150 mg

Mechanism of Action

Tolperisone works via multiple mechanisms:

  1. Neuromuscular Blocking: It inhibits abnormal reflex activity in the spinal cord and brainstem.

  2. Muscle Relaxation: Relieves hypertonicity and spasticity while allowing voluntary muscle movements.

  3. Vasodilatory Effect: Enhances blood circulation in affected tissues, aiding recovery and reducing pain.

This triple action makes it highly effective for controlling muscle stiffness, spasms, and neuropathic pain.

Uses of TOPERITIME 150 (Tolperisone Hydrochloride 150 mg Tablets)

TOPERITIME 150 is prescribed for:

  • Spasticity after Stroke – Helps patients regain mobility.

  • Multiple Sclerosis (MS) – Reduces muscle stiffness and spasms.

  • Spinal Cord Injuries & Diseases – Improves flexibility and reduces pain.

  • Post-operative Muscle Spasms – After orthopedic or neurosurgical procedures.

  • Cervical & Lumbar Spondylosis – Relieves stiffness in neck and back.

  • Fibromyalgia & Chronic Pain Syndromes – Reduces muscle hyperactivity.

  • Musculoskeletal Disorders – Like low back pain, sciatica, and arthritis-related stiffness.

Dosage and Administration

  • Typical Dose: 150 mg, 2 to 3 times daily (as advised by physician).

  • Route: Oral – swallow with water after meals to reduce gastric irritation.

  • Individual Adjustment: Dose may be modified depending on patient’s age, severity, and medical condition.

 Do not self-medicate. Always follow your doctor’s prescription.

Side Effects of Tolperisone 150 mg Tablets

Most patients tolerate Tolperisone well, but some may experience:

  • Headache or dizziness

  • Nausea, vomiting, or abdominal pain

  • Hypotension (low blood pressure)

  • Fatigue or muscle weakness

  • Allergic reactions (rash, itching, swelling – rare)

Seek immediate medical attention if you notice severe allergic reactions or persistent side effects.

Precautions & Warnings

  • Pregnancy & Breastfeeding: Use only if prescribed by a doctor.

  • Myasthenia Gravis: Contraindicated in patients with this condition.

  • Liver & Kidney Impairment: Use cautiously, with medical monitoring.

  • Alcohol: Avoid as it increases dizziness and drowsiness.

  • Driving & Machinery: Use caution until you know how the drug affects you.

Drug Interactions

Tolperisone may interact with:

  • Other muscle relaxants – Can increase muscle weakness.

  • CNS depressants (alcohol, sleeping pills, sedatives) – Can cause excessive drowsiness.

  • NSAIDs & analgesics – May alter drug metabolism.

Always inform your doctor about all medicines, supplements, or herbal products you are taking.

Why Buy TOPERITIME 150 from Steris Healthcare Pvt Ltd?

Steris Healthcare Pvt Ltd is a trusted pharmaceutical leader in India known for:

  • WHO-GMP certified manufacturing ensuring top-quality medicines.

  • Affordable pricing making treatments accessible to all.

  • Wide product portfolio covering pharmaceuticals and healthcare needs.

  • Pan-India presence ensuring easy availability.

  • Ethical and customer-centric practices trusted by healthcare professionals.

By choosing TOPERITIME 150 from Steris Healthcare, patients receive a product that is safe, effective, and reliable.

FAQs on Tolperisone 150 mg Tablets (TOPERITIME 150)

Q1. What is Tolperisone 150 mg used for?
It is used to treat muscle stiffness, spasms, and spasticity in conditions like stroke, spinal cord injuries, and multiple sclerosis.

Q2. Can I take Tolperisone 150 daily?
Yes, but only as prescribed by a doctor. Long-term use should be monitored.

Q3. Does Tolperisone cause sleepiness?
No, it usually does not cause significant sedation, unlike other muscle relaxants.

Q4. Can Tolperisone be taken with painkillers?
Yes, but only under medical advice to avoid drug interactions.

Q5. Is Tolperisone safe for elderly patients?
Yes, but dose adjustment may be required depending on health condition.

Q6. How long should Tolperisone be taken?
Treatment duration depends on the underlying condition and your doctor’s advice.

Q7. Can I drink alcohol while taking Tolperisone?
No, alcohol should be avoided as it can worsen dizziness and side effects.

Conclusion

TOPERITIME 150 (Tolperisone Hydrochloride Tablets 150 mg) is a highly effective muscle relaxant that relieves spasticity and stiffness without excessive drowsiness. It plays a vital role in neurological rehabilitation and musculoskeletal pain management.Choosing Steris Healthcare Pvt Ltd ensures trusted quality, proven efficacy, and affordable prices, making it the right choice for patients and healthcare professionals alike.

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