SULTAMYLIN 375 & Sultamicillin (375mg)Key Ingredients and Benefits, Indications for Use Etc....
Aug 12, 2024
SULTAMYLIN 375
Sultamicillin (375mg)
SULTAMYLIN 375 contains Sultamicillin (375mg), which is a powerful antibiotic medication designed to treat a broad spectrum of bacterial infections. As a combination of two active ingredients, ampicillin and sulbactam, it offers enhanced efficacy against resistant strains of bacteria. The synergy between these two components allows SULTAMYLIN 375 to overcome common bacterial defense mechanisms, making it an essential tool in combating infections that might otherwise be challenging to treat.
How Does Sultamicillin Work?
Sultamicillin is a mutual prodrug, combining ampicillin and sulbactam in a single molecule. When ingested, it breaks down in the body into these two components:
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Ampicillin: This is a broad-spectrum penicillin antibiotic that works by inhibiting the synthesis of bacterial cell walls. By binding to specific penicillin-binding proteins (PBPs) inside the bacterial cell wall, ampicillin prevents the bacteria from forming a vital component of their structure, leading to cell lysis and death.
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Sulbactam: This is a β-lactamase inhibitor that helps protect ampicillin from being degraded by β-lactamase enzymes produced by some bacteria. These enzymes are a common resistance mechanism in bacteria, which can render many antibiotics ineffective. By inhibiting these enzymes, sulbactam enhances the effectiveness of ampicillin, allowing it to act against β-lactamase-producing strains.
Uses of SULTAMYLIN 375
SULTAMYLIN 375 is used to treat a wide range of bacterial infections, including but not limited to:
- Respiratory Tract Infections: Effective against both upper and lower respiratory tract infections, including bronchitis, sinusitis, and pneumonia.
- Urinary Tract Infections (UTIs): Commonly prescribed for UTIs caused by susceptible bacteria.
- Skin and Soft Tissue Infections: Beneficial in treating cellulitis, abscesses, and wound infections.
- Gynecological Infections: Including pelvic inflammatory disease and post-surgical infections.
- Gastrointestinal Infections: Used in treating infections like typhoid fever and other gastrointestinal bacterial diseases.
Dosage and Administration
The recommended dosage of SULTAMYLIN 375 depends on the severity and type of infection, as well as the patient’s age and overall health. The usual adult dose is one 375 mg tablet twice daily. However, the dosage may be adjusted by a healthcare provider based on specific patient needs. It is crucial to follow the prescribed dosage regimen precisely to ensure the effectiveness of the treatment and to prevent the development of antibiotic resistance.
- Administration: SULTAMYLIN 375 should be taken with or without food. However, taking it with a meal may help reduce the potential for gastrointestinal discomfort.
Side Effects of SULTAMYLIN 375
Like all medications, SULTAMYLIN 375 may cause side effects in some patients. Common side effects include:
- Gastrointestinal Issues: Nausea, vomiting, diarrhea, and abdominal pain are the most commonly reported side effects.
- Allergic Reactions: Some individuals may experience allergic reactions such as rash, itching, or hives. In rare cases, severe allergic reactions like anaphylaxis may occur, which requires immediate medical intervention.
- Superinfection: Prolonged use of SULTAMYLIN 375 may lead to superinfection with non-susceptible organisms, including fungi.
- Hematologic Effects: Rarely, the medication may cause changes in blood cell counts, including leukopenia, thrombocytopenia, or anemia.
- Liver Enzyme Alterations: Mild elevations in liver enzymes (ALT, AST) can occur but are usually reversible upon discontinuation of the drug.
It is essential to report any persistent or severe side effects to a healthcare provider promptly.
Safety Information and Precautions
Before starting treatment with SULTAMYLIN 375, patients should inform their healthcare provider about any known allergies, especially to penicillins or cephalosporins. This medication should be used with caution in individuals with:
- Kidney Impairment: Dosage adjustment may be necessary for patients with renal impairment to prevent drug accumulation and toxicity.
- Liver Disease: Patients with liver disease should be monitored closely, as the drug is metabolized in the liver.
- Pregnancy and Lactation: Sultamicillin is generally considered safe during pregnancy, but it should only be used if clearly needed. It is excreted in breast milk, so caution is advised when administering it to breastfeeding mothers.
- History of Gastrointestinal Disease: Particularly colitis, as antibiotic therapy can increase the risk of Clostridium difficile-associated diarrhea.
Price of SULTAMYLIN 375 in India
The cost of SULTAMYLIN 375 can vary depending on the brand, location, and pharmacy. On average, a pack of 10 tablets may range from INR 200 to INR 400. Prices may vary, and it is advisable to check with local pharmacies or online platforms for the most current pricing.
Conclusion
SULTAMYLIN 375 is a versatile and potent antibiotic that offers a reliable option for treating a wide range of bacterial infections. Its unique combination of ampicillin and sulbactam enhances its efficacy, especially against resistant bacterial strains. However, as with all antibiotics, it is crucial to use this medication responsibly, adhering to prescribed dosages and durations to prevent the development of resistance. Patients should always consult with their healthcare provider for personalized advice and report any side effects or concerns during treatment. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.
For further information
Email: info@sterispharma.com / contact@sterispharma.com
Call/WhatsApp: 7877551268, 7849827488
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