Introduction

SACUSMART 200 is a prescription medicine containing Sacubitril and Valsartan Tablets, specially formulated for the treatment of heart failure with reduced ejection fraction (HFrEF). This innovative dual-acting therapy is classified as an angiotensin receptor neprilysin inhibitor (ARNI) and is widely recommended by cardiologists to improve survival, reduce hospitalizations, and enhance the quality of life in heart failure patients.

Composition

• Active Ingredients:

  • Sacubitril – Neprilysin inhibitor

  • Valsartan – Angiotensin II receptor blocker (ARB)

• Formulation: Film-coated tablet

• Brand Name: SACUSMART 200

What is Sacubitril and Valsartan?

Sacubitril and Valsartan is a combination medicine designed to improve heart function in patients with chronic heart failure.

• Sacubitril enhances the effects of natriuretic peptides by inhibiting neprilysin, leading to vasodilation, natriuresis (salt excretion), and reduced cardiac stress.

• Valsartan blocks the angiotensin II receptor, lowering blood pressure and preventing harmful effects of the renin-angiotensin system.

Together, they provide a synergistic benefit in reducing strain on the heart and improving outcomes in patients with left ventricular dysfunction.

Uses of Sacubitril and Valsartan Tablets

SACUSMART 200 is prescribed for:

• Treatment of heart failure with reduced ejection fraction (HFrEF)

• Reducing the risk of cardiovascular death and hospitalization in heart failure patients

• Improving symptoms such as shortness of breath, fatigue, and swelling

• Enhancing exercise capacity and quality of life

• Sometimes used in patients not responding adequately to ACE inhibitors or ARBs alone

Dosage and Administration

• Typical Dose: One tablet twice daily (as per doctor’s prescription)

• Route: Oral

• Dose Adjustment: May be required for patients with kidney impairment, liver dysfunction, or low blood pressure

• Important:

  • Do not take with ACE inhibitors (must have a 36-hour gap after stopping ACE inhibitors)

  • Complete adherence to dosage is essential for effectiveness

Side Effects of Sacubitril and Valsartan

While effective, SACUSMART 200 may cause some side effects:

• Common:

  • Low blood pressure (hypotension)

  • Dizziness or fainting

  • Increased potassium levels (hyperkalemia)

  • Cough

• Less Common:

  • Kidney function impairment

  • Fatigue

  • Nausea

• Serious but Rare:

  • Angioedema (swelling of face, lips, throat)

  • Severe allergic reactions

Seek immediate medical help if symptoms of allergic reaction or angioedema occur.

Precautions

• Do not take if allergic to sacubitril, valsartan, or other ARBs.

• Avoid use with ACE inhibitors or aliskiren (in diabetic patients).

• Monitor blood pressure, potassium levels, and kidney function regularly.

• Use cautiously in pregnancy and breastfeeding (not generally recommended).

• Avoid alcohol and high-potassium diet unless advised by the doctor.

Drug Interactions

• Avoid combining with ACE inhibitors, aliskiren, potassium supplements, NSAIDs, and lithium.

• Always inform your doctor about any other medicines or supplements you are taking.

Why Choose Steris Healthcare Pvt Ltd for SACUSMART 200?

Steris Healthcare Pvt Ltd ensures that SACUSMART 200 delivers the highest standards of safety, efficacy, and affordability.

• WHO-GMP Certified Manufacturing Units

• Stringent Quality Control Measures

• Affordable & Accessible Pricing

• Trusted by Healthcare Professionals Across India

• Wide Product Range for Cardiac Care

By choosing Steris Healthcare, patients and doctors are assured of reliable formulations, ethical practices, and nationwide availability.

Frequently Asked Questions (FAQs)

1. What is SACUSMART 200 used for?
It is used to treat chronic heart failure with reduced ejection fraction, improving survival and reducing hospitalizations.

2. How should I take Sacubitril and Valsartan Tablets?
Take exactly as prescribed, usually one tablet twice daily, with or without food.

3. Can I take it with ACE inhibitors?
No. A minimum 36-hour gap is required after stopping ACE inhibitors before starting SACUSMART 200.

4. Is SACUSMART 200 safe in pregnancy?
No, it is not recommended during pregnancy or breastfeeding. Always consult a doctor.

5. What should I do if I miss a dose?
Take it as soon as you remember. If it’s close to the next dose, skip the missed one. Do not double the dose.

6. How long do I need to take Sacubitril and Valsartan?
It is usually a long-term treatment for heart failure, as advised by your doctor.

Conclusion

Sacubitril and Valsartan Tablets (SACUSMART 200) represent a modern and effective therapy for heart failure management, reducing hospitalizations and improving patient survival. With the assurance of Steris Healthcare Pvt Ltd, patients receive a safe, high-quality, and affordable treatment option backed by trusted pharmaceutical expertise.