Introduction

Phenoxymethylpenicillin Potassium Tablets IP 250 mg, marketed under the brand name PENITRIAD 250, are a widely used antibiotic belonging to the penicillin class. This medicine is prescribed for the treatment and prevention of bacterial infections. Known for its effectiveness, safety profile, and affordability, PENITRIAD 250 is a trusted choice in clinical practice.

Composition

• Active Ingredient: Phenoxymethylpenicillin Potassium IP 250 mg

• Formulation: Film-coated oral tablet

• Brand Name: PENITRIAD 250

What is Phenoxymethylpenicillin Potassium?

Phenoxymethylpenicillin Potassium is a penicillin antibiotic used primarily for the treatment of mild-to-moderate infections caused by susceptible bacteria. It is acid-stable, allowing effective oral administration, and is often prescribed for respiratory tract infections, skin infections, and for prophylaxis against rheumatic fever.

Mechanism of Action

Phenoxymethylpenicillin Potassium works by:

• Inhibiting bacterial cell wall synthesis

• Binding to penicillin-binding proteins (PBPs)

• Disrupting the formation of peptidoglycan, an essential structural component of the bacterial cell wall

• Leading to cell lysis and death of susceptible bacteria

This bactericidal action makes it a reliable antibiotic for treating various bacterial infections.

Uses of Phenoxymethylpenicillin Potassium Tablets IP 250 mg

PENITRIAD 250 is prescribed for:

• Respiratory Tract Infections: Pharyngitis, tonsillitis, otitis media, and sinusitis

• Skin and Soft Tissue Infections: Cellulitis, impetigo, erysipelas

• Dental Infections: Dental abscesses, prophylaxis in dental procedures

• Prophylaxis of Rheumatic Fever

• Scarlet Fever and Streptococcal Infections

• Mild to moderate bacterial infections caused by penicillin-sensitive organisms

Dosage and Administration

• Adults: Typical dose is 250–500 mg every 6–8 hours, depending on severity of infection

• Children: Dosage is based on body weight and age (commonly 25–50 mg/kg/day in divided doses)

• Route: Oral administration

• Important: Dosage must be taken as prescribed by the physician. Completing the full course is essential to prevent resistance.

Side Effects of Phenoxymethylpenicillin Potassium

Most patients tolerate PENITRIAD 250 well, but possible side effects include:

• Common:

  • Nausea

  • Vomiting

  • Diarrhea

  • Abdominal discomfort

• Less Common:

  • Rash or allergic skin reactions

  • Headache

  • Dizziness

• Rare but Serious:

  • Severe allergic reactions (anaphylaxis)

  • Stevens-Johnson syndrome

  • Blood disorders (rare cases)

Seek immediate medical help if signs of allergy (swelling, rash, difficulty breathing) occur.

Precautions

• Inform your doctor if you are allergic to penicillin or cephalosporins.

• Use with caution in patients with kidney impairment.

• Inform the doctor about any ongoing medications (as interactions may occur with methotrexate, anticoagulants, and oral contraceptives).

• Avoid alcohol during treatment for best results.

• Safe in pregnancy and lactation under medical supervision.

Drug Interactions

• May interact with methotrexate, oral contraceptives, anticoagulants, probenecid, and allopurinol.

• Always inform your doctor of any medicines or supplements you are taking.

Why Choose Steris Healthcare Pvt Ltd for PENITRIAD 250?

Steris Healthcare Pvt Ltd is a leading pharmaceutical company known for delivering quality, affordable, and reliable medicines across India. Choosing PENITRIAD 250 from Steris ensures:

• WHO-GMP Certified Manufacturing Standards

• Strict Quality Control & Safety Assurance

• Wide Availability Across India

• Affordable Pricing Without Compromising Quality

• Trust of Healthcare Professionals Nationwide

Steris Healthcare focuses on patient safety, ethical practices, and accessibility, making it a trusted brand in the pharmaceutical industry.

Frequently Asked Questions (FAQs)

1. What is Phenoxymethylpenicillin Potassium 250 mg used for?
It is used to treat bacterial infections of the throat, ear, skin, and soft tissues, and to prevent rheumatic fever.

2. Can I take PENITRIAD 250 without a doctor’s prescription?
No. This is a prescription-only medicine and should be taken under medical supervision.

3. How long should I take Phenoxymethylpenicillin Potassium?
The duration depends on the infection. Complete the full course even if symptoms improve, unless advised otherwise by your doctor.

4. Is it safe in pregnancy and breastfeeding?
Yes, generally safe when prescribed by a doctor. Always consult before use.

5. Can PENITRIAD 250 cause diarrhea?
Yes, mild diarrhea is a common side effect. However, if severe or persistent, consult your doctor.

6. What should I do if I miss a dose?
Take it as soon as you remember. If it’s almost time for the next dose, skip the missed one. Do not double the dose.

Conclusion

Phenoxymethylpenicillin Potassium Tablets IP 250 mg (PENITRIAD 250) are an effective and trusted antibiotic for the treatment and prevention of bacterial infections. With a strong safety record and reliable results, it remains a preferred choice among healthcare professionals. Buying from Steris Healthcare Pvt Ltd guarantees quality, affordability, and nationwide availability—making it the right choice for patients and healthcare providers.