Rabeprazole Sodium and Ondansetron Tablets – Uses, Dosage, Side Effects and Benefits
Sep 13, 2025
Introduction
RABISTRUM ODIN is a combination tablet containing Rabeprazole Sodium and Ondansetron. This medication is designed to relieve nausea and vomiting while protecting the stomach lining in patients who are at risk of gastrointestinal irritation.It is commonly prescribed for chemotherapy-induced nausea, post-operative nausea, and acid-related disorders where a proton pump inhibitor like Rabeprazole is required alongside antiemetic therapy with Ondansetron.
Composition of RABISTRUM ODIN
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Rabeprazole Sodium – Proton pump inhibitor for gastric protection
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Ondansetron – 5-HT3 receptor antagonist for antiemetic effect
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Dosage Form: Tablet
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Brand Name: RABISTRUM ODIN
Mechanism of Action
Rabeprazole Sodium
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Works by inhibiting gastric proton pumps, which reduces stomach acid secretion.
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Helps prevent gastric irritation, ulcers, and reflux symptoms during treatment with medications that can upset the stomach.
Ondansetron
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A serotonin 5-HT3 receptor antagonist
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Blocks the action of serotonin in the gut and central nervous system, which helps control nausea and vomiting.
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Effective in chemotherapy-induced, radiation-induced, and post-operative nausea.
Uses of Rabeprazole Sodium and Ondansetron Tablets
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Prevention and treatment of chemotherapy-induced nausea and vomiting
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Management of post-operative nausea and vomiting
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Relief from acid reflux, heartburn, and gastric irritation
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Protection of the stomach during long-term medication therapy
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Supportive therapy in patients with gastritis or ulcer risk while managing nausea
Method of Administration
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Route: Oral
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Dosage: As prescribed by the physician based on condition severity
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Instructions: Take the tablet with water, preferably before meals.
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Swallow the tablet whole; do not crush or chew.
Dosage Strength
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Rabeprazole Sodium: Varies depending on prescription
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Ondansetron: Typically 4 mg or as prescribed
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Dosage may vary based on patient age, condition, and medical history
Side Effects
While RABISTRUM ODIN is generally well-tolerated, some side effects may occur:
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Headache or dizziness
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Constipation or diarrhea
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Fatigue or weakness
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Abdominal pain or bloating
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Rare: Allergic reactions, changes in heart rhythm, or liver enzyme alterations
Most side effects are mild and temporary. Consult your doctor if severe reactions occur.
Contraindications
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Hypersensitivity to Rabeprazole Sodium or Ondansetron
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Severe liver impairment
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History of heart rhythm disorders (Ondansetron caution)
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Pregnancy and breastfeeding should be evaluated by a doctor
Drug Interactions
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May interact with other medications metabolized by the liver
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Caution with anticoagulants, antiarrhythmic drugs, or other antiemetics
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Inform your doctor about all medications and supplements before starting therapy
Clinical Studies
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Clinical studies demonstrate that combining Rabeprazole Sodium and Ondansetron is effective in preventing nausea and vomiting while protecting gastric mucosa.
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Ondansetron has been proven effective in post-chemotherapy and post-operative antiemetic therapy.
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Rabeprazole ensures stomach protection from NSAIDs or stress-related gastric acid secretion.
Why Choose Steris Healthcare Pvt. Ltd.
Steris Healthcare Pvt. Ltd. is a trusted name in pharmaceuticals due to:
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WHO-GMP certified manufacturing, ensuring quality and safety
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Affordable and reliable medicines for patients across India
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Ethical practices and patient-focused solutions
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Extensive portfolio including gastroprotective and antiemetic therapies
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Commitment to innovation and consistent quality
By choosing RABISTRUM ODIN from Steris Healthcare, patients receive safe, effective, and high-quality therapy.
FAQs:
Q1: What are Rabeprazole Sodium and Ondansetron tablets used for?
A: RABISTRUM ODIN (Rabeprazole Sodium and Ondansetron tablets) is used for preventing nausea and vomiting caused by chemotherapy, surgery, or other medical conditions, and for protecting the stomach from acid-related disorders.
Q2: How does RABISTRUM ODIN work?
A: Rabeprazole Sodium and Ondansetron tablets work through a dual-action mechanism. Ondansetron controls nausea and vomiting by blocking serotonin receptors, while Rabeprazole reduces stomach acid secretion, helping protect the gastric lining.
Q3: How should Rabeprazole Sodium and Ondansetron tablets be taken?
A: RABISTRUM ODIN capsules should be taken orally with water, preferably before meals, as prescribed by your doctor. Do not crush or chew the tablet.
Q4: What are the common side effects of Rabeprazole Sodium and Ondansetron tablets?
A: Some common side effects of RABISTRUM ODIN include headache, constipation, diarrhea, dizziness, fatigue, and mild abdominal pain. Most side effects are mild and temporary.
Q5: Can Rabeprazole Sodium and Ondansetron tablets be used in pregnancy?
A: RABISTRUM ODIN should only be used under doctor's supervision during pregnancy. Safety and dosage must be carefully evaluated by a healthcare professional.
Conclusion
Rabeprazole Sodium and Ondansetron Tablets is a dual-action therapy that combines antiemetic and gastroprotective effects. It is effective for nausea, vomiting, and stomach acid protection during chemotherapy, surgery, or high-risk gastric conditions.With Steris Healthcare Pvt. Ltd., patients can rely on trusted quality, affordability, and safe medication to manage their symptoms effectively.
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