Introduction

RABISTRUM ACF is a combination capsule containing Aceclofenac 200 mg SR and Rabeprazole 20 mg. This powerful combination is specifically designed to provide effective pain relief and protect the stomach from NSAID-induced irritation. It is widely prescribed for musculoskeletal pain, arthritis, and inflammatory conditions, where long-term Aceclofenac therapy may otherwise cause gastric discomfort or ulceration. Rabeprazole, a proton pump inhibitor, safeguards the stomach lining while Aceclofenac reduces pain and inflammation.

Composition of RABISTRUM ACF

• Aceclofenac SR 200 mg – Anti-inflammatory and analgesic agent

• Rabeprazole 20 mg – Proton pump inhibitor for gastric protection

• Dosage Form: Capsules

• Brand Name: RABISTRUM ACF

Mechanism of Action

Aceclofenac:

• A non-steroidal anti-inflammatory drug (NSAID)

• Inhibits COX-1 and COX-2 enzymes, reducing prostaglandin production

• Provides pain relief, an anti-inflammatory effect, and reduced swelling

Rabeprazole:

• A proton pump inhibitor (PPI) that suppresses gastric acid secretion

• Protects the stomach from NSAID-induced gastritis, ulcers, and dyspepsia

• Ensures safe long-term Aceclofenac therapy

Indications of RABISTRUM ACF

• Osteoarthritis – Pain and stiffness relief

• Rheumatoid arthritis – Reduces inflammation and joint pain

• Musculoskeletal pain – Effective in sprains, strains, and back pain

• Post-surgical pain management – Reduces inflammation while protecting the stomach

• Other inflammatory conditions requiring long-term NSAID therapy

Uses of Rabeprazole Aceclofenac Capsules

RABISTRUM ACF uses include:

• Aceclofenac 200 mg SR + Rabeprazole 20 mg helps in pain reduction without causing stomach irritation.

• Effective in managing chronic arthritis and joint disorders.

• Provides dual-action therapy: analgesic effect of Aceclofenac and gastroprotection from Rabeprazole.

Method of Administration

• Route: Oral

• Dosage: Usually 1 capsule daily or as prescribed by the doctor

• Instructions: Take with water, preferably after meals to minimize gastric discomfort.

• Do not crush or chew the sustained-release capsule.

Dosage Strength

• Aceclofenac: 200 mg SR

• Rabeprazole: 20 mg

• Dosage may vary depending on the severity of pain and the patient's condition

Side Effects of RABISTRUM ACF

While generally well-tolerated, some patients may experience:

Aceclofenac-related side effects:

• Nausea, vomiting

• Abdominal pain, dyspepsia

• Headache, dizziness

• Skin rash or itching

• Rare: Gastric ulcers, liver enzyme elevation

Rabeprazole-related side effects:

• Diarrhea or constipation

• Flatulence, bloating

• Headache or fatigue

• Rare: Vitamin B12 deficiency with long-term use, hypomagnesemia

Most side effects are mild and resolve on their own. Consult your doctor if severe or persistent symptoms occur.

Contraindications

• Hypersensitivity to Aceclofenac, Rabeprazole, or other NSAIDs

• Active peptic ulcer disease

• Severe liver or kidney impairment

• Pregnancy (especially the third trimester)

• Patients with bleeding disorders or under anticoagulant therapy

Drug Interactions

• Anticoagulants (Warfarin) – Increased risk of bleeding

• Other NSAIDs – May increase gastrointestinal toxicity

• CYP2C19 inhibitors – Can affect Rabeprazole metabolism

• Diuretics – May enhance hypokalemia risk

• Corticosteroids – Increased risk of gastric irritation

Clinical Studies

• Clinical trials demonstrate Aceclofenac SR + Rabeprazole 20 mg provides effective pain relief in osteoarthritis, rheumatoid arthritis, and musculoskeletal disorders.

• Studies show reduced incidence of NSAID-induced gastric complications with Rabeprazole co-administration.

• Sustained-release formulation ensures consistent pain control throughout the day.

• Well-tolerated in long-term use with fewer gastrointestinal adverse events compared to Aceclofenac monotherapy.

Why Choose Steris Healthcare Pvt. Ltd.?

• High-quality manufacturing under WHO-GMP standards

• Affordable and effective medicines for patients across India

• Extensive distribution network ensuring availability

• Ethical and patient-centric approach

• Trusted by doctors and healthcare providers nationwide

By choosing RABISTRUM ACF from Steris Healthcare, patients receive safe, effective, and reliable pain management therapy.

FAQs

Q1: What is RABISTRUM ACF used for?
A: It is used for pain, inflammation, and gastric protection in musculoskeletal disorders and arthritis.

Q2: What is the composition of RABISTRUM ACF?
A: Aceclofenac 200 mg SR + Rabeprazole 20 mg per capsule.

Q3: How should RABISTRUM ACF be taken?
A: Swallow the capsule with water, preferably after meals. Do not crush or chew.

Q4: Can it cause stomach problems?
A: Rabeprazole protects the stomach, reducing the risk of NSAID-induced ulcers and gastritis.

Q5: Can elderly patients use it?
A: Yes, with caution, especially if they have liver, kidney, or heart issues.

Q6: What are the side effects?
A: Nausea, headache, abdominal pain, diarrhea, dizziness, or skin rash. Rarely, gastric ulcers or vitamin deficiencies may occur.

Conclusion

Aceclofenac 200 mg SR + Rabeprazole 20 mg capsules is a dual-action therapy that effectively manages pain and inflammation while protecting the stomach from NSAID-related irritation. For safe, high-quality, and affordable medication, Steris Healthcare Pvt. Ltd. is a trusted choice, ensuring patients get effective pain relief with minimal gastrointestinal risk.