Pregabalin and Methylcobalamin Tablets 

When it comes to nerve pain and neuropathy, Pregabalin and Methylcobalamin Tablets offer a powerful and effective combination therapy. Under the brand name Pregabrial M Forte 75/1500, this dual-action formulation blends pregabalin 75 mg with methylcobalamin 1,500 mcg, delivering not only symptomatic relief but also long-term nerve repair. Ideal for individuals dealing with diabetic neuropathy, post-herpetic neuralgia, and other nerve disorders, this therapy addresses both pain management and nerve regeneration in one comprehensive treatment.

What Are Pregabalin and Methylcobalamin Tablets (Pregabrial M Forte 75/1500)?

Pregabrial M Forte 75/1500 combines two clinically proven active ingredients:

• Pregabalin 75 mg: A derivative of the neurotransmitter GABA, pregabalin acts by reducing abnormal nerve signals that cause pain, tingling, or burning—making it ideal for neuropathic pain relief.
   
• Methylcobalamin 1,500 mcg: A bioactive form of vitamin B₁₂ known to support nerve regeneration, improve myelin sheath stability, and enhance overall nerve function.
   

Together, pregabalin and methylcobalamin tablets offer dual benefits: quick relief (via pregabalin) and long-term nerve health (via methylcobalamin).

Key Benefits of Pregabrial M Forte 75/1500

Pregabalin and Methylcobalamin Tablets provide a multi-layered advantage:

1. Fast Pain Relief
   Pregabalin blocks excess neurotransmitter release, alleviating neuropathic pain, burning, and tingling within hours or days.
    
2. Nerve Repair and Regeneration
   Methylcobalamin helps repair damaged nerve fibers, promote myelin restoration, and improve signal conduction.
    
3. Improved Sensory Function
   This combination can help patients regain sensation, reduce numbness, and improve fine motor control.
    
4. Reduced Reliance on Opioids
   Effective nerve pain control means fewer side effects associated with opioid or NSAID use.
    
5. Comprehensive Neuropathy Management
   Addressing both symptomatic and structural nerve issues ensures a more holistic treatment than single-ingredient drugs.
    

Pregabalin and Methylcobalamin Tablets Uses

Pregabrial M Forte 75/1500 is commonly prescribed for:

• Diabetic neuropathy – relieving burning, tingling, and nocturnal pain.
   
• Post-herpetic neuralgia – after shingles or herpes zoster infections.
   
• Peripheral neuropathy – from causes like chemotherapy or infections.
   
• Nutritional neuropathy – where vitamin B₁₂ deficiency exacerbates symptoms.
   
• Fibromyalgia (off-label) – when accompanied by nerve pain components.
   

Doctors may also recommend it for mixed nerve-pain syndromes or chronic back-related radiculopathy featuring neuropathic elements.

How It Works

1. Pregabalin Mechanism

Pregabalin binds to the α₂δ subunit of voltage-gated calcium channels in the central nervous system. This reduces calcium influx, lowering the release of excitatory neurotransmitters like glutamate and substance P—resulting in diminished neuropathic pain signals.

2. Methylcobalamin Benefits

Unlike cyanocobalamin, methylcobalamin is readily used by the body to support DNA synthesis, myelin repair, nerve conduction, and neurotransmitter metabolism. It helps restore axonal integrity and enhances neurological function over time.

Dosage and Directions for Use

Typically prescribed for adults:

• Pregabalin 75 mg taken twice daily (morning and evening) with or without food.
   
• Methylcobalamin 1,500 mcg taken with the pregabalin dose—ideally at regular intervals.
   

Usual dosing schedule:

• One tablet in the morning, with food.
   
• One tablet in the evening, with food.
   

Physicians may adjust dosage based on severity and patient response. Importantly, pregabalin and methylcobalamin tablets must be taken exactly as prescribed—avoiding abrupt discontinuation, which can lead to withdrawal symptoms.
 

Possible Side Effects of Pregabalin and Methylcobalamin Tablets.

While generally well-tolerated, you may experience:

Common Side Effects

• Dizziness or light-headedness
   
• Drowsiness or fatigue
   
• Nausea or dry mouth
   
• Edema (leg swelling)
   
• Weight gain
   
• Mild gastrointestinal discomfort
   

Less Common but Notable Effects

• Blurred vision or coordination issues
   
• Mood changes, including irritability or depression
   
• Headache or increased appetite
   
• Injection site issues (if using injectable methylcobalamin)
   

Serious reactions are rare, but include:

• Allergic rash, swelling, or difficulty breathing
   
• Suicidal thoughts or depressive behavior (monitor carefully)
   
• Severe peripheral edema or extreme fatigue
   

These side effects are generic to pregabalin and methylcobalamin tablets use, and not unique to Pregabrial M Forte.

Why Choose Steris Healthcare For Pregabalin and Methylcobalamin Tablets?

Steris Healthcare Pvt Ltd is a well-known name in the pharmaceutical sector because of its dedication to providing high-quality, scientifically supported, and patient-centered healthcare solutions. When it comes to Pregabalin with Methylcobalamin Tablets, Steris Healthcare assures that the combination is therapeutically effective and prepared in strict accordance with international quality standards. The brand's formulation, also known as Pregabrial M Forte 75/1500, is meticulously formulated with pregabalin 75 mg and methylcobalamin 1500 mcg, both of which are well-known for their therapeutic effectiveness in treating neuropathic pain and encouraging nerve regeneration.

Choosing Steris Healthcare for this nerve care combination ensures access to DCGI-approved compositions manufactured in WHO-GMP accredited facilities under stringent quality assurance processes. The brand emphasizes precise dosage, excellent bioavailability, and stable formulations to provide consistent outcomes and patient satisfaction. Furthermore, Steris Healthcare provides extensive assistance to its distributors and franchise partners by assuring 100% stock availability, attractive packaging, and timely delivery throughout India.