Enzalutamide 160 mg tablet is a potent oral medication used for the treatment of advanced prostate cancer, particularly metastatic castration-resistant prostate cancer (mCRPC) and non-metastatic castration-resistant prostate cancer (nmCRPC). As a second-generation androgen receptor inhibitor, Enzalutamide blocks the effects of male hormones (androgens), thereby slowing the growth and spread of prostate cancer.

This article explores in detail the uses, benefits, enzalutamide 160 mg side effects, dosage, and tab enzalutamide 160 mg price in India, making it a valuable guide for patients, caregivers, and healthcare professionals.

What Is Enzalutamide 160 mg?

Enzalutamide 160 mg is an oral prescription medication primarily indicated for:

• Metastatic Castration-Resistant Prostate Cancer (mCRPC)

• Non-Metastatic Castration-Resistant Prostate Cancer (nmCRPC)

• Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
   

It works by blocking androgen receptors on prostate cancer cells, thereby preventing testosterone and other male hormones from stimulating tumor growth. It is commonly used in combination with androgen deprivation therapy (ADT), such as luteinizing hormone-releasing hormone (LHRH) agonists.

Enzalutamide 160 mg Uses

The most well-established enzalutamide 160 mg uses include:

1. Castration-Resistant Prostate Cancer (CRPC)

Prostate cancer that progresses despite low testosterone levels (after surgical or medical castration) is called CRPC. Enzalutamide effectively delays disease progression in both metastatic and non-metastatic CRPC.

2. Hormone-Sensitive Prostate Cancer (HSPC)

In newly diagnosed patients with metastatic hormone-sensitive prostate cancer, Enzalutamide is used in combination with ADT to extend overall survival and delay disease progression.

3. Delaying Metastasis

In patients with non-metastatic prostate cancer, Enzalutamide has shown to significantly delay the onset of metastasis, buying patients valuable time before the disease spreads.

Enzalutamide 160 mg Tablet Benefits

The enzalutamide 160 mg tablet is preferred by oncologists for its effectiveness, safety profile, and survival benefits. Key benefits include:

1. Increased Overall Survival

Clinical trials like PROSPER, PREVAIL, and AFFIRM have demonstrated Enzalutamide’s ability to improve overall survival in both early-stage and advanced prostate cancer patients.

2. Delayed Cancer Progression

Enzalutamide slows the spread of cancer cells by interfering with androgen receptor signaling pathways. This makes it effective in halting disease progression in hormone-resistant forms of prostate cancer.

3. Convenient Oral Administration

Unlike chemotherapy or injectable therapies, Enzalutamide is taken orally, offering patients a convenient at-home treatment option.

4. Reduced Risk of Skeletal Events

It lowers the chances of bone fractures, spinal cord compression, and other skeletal-related complications of metastatic prostate cancer.

5. Improved Quality of Life

Patients report better pain control, urinary function, and overall wellbeing while on Enzalutamide therapy.
 

Tab Enzalutamide 160 mg Dosage and Administration

The standard recommended dosage is:

• Tab Enzalutamide 160 mg taken once daily, preferably at the same time each day.
   
• Typically administered as four 40 mg capsules or a single 160 mg tablet.
   

Administration Tips:

• With or without food
   
• Swallow the tablet whole with water; do not crush or chew
   
• Continue androgen deprivation therapy (e.g., LHRH agonists) as prescribed
   
• Do not stop the medication without consulting your oncologist
   

Missed Dose:

If you miss a dose, take it as soon as you remember the same day. Skip it if it's the next day—do not double the dose.

Enzalutamide 160 mg Side Effects

Like all medications, enzalutamide 160 mg side effects may occur, though not everyone experiences them. These side effects vary in intensity and may be temporary or persistent depending on the patient’s condition.

Common Side Effects:

• Fatigue or weakness
   
• Back pain
   
• Hot flashes
   
• High blood pressure (hypertension)
   
• Constipation
   
• Joint or muscle pain
   
• Increased risk of falls
   

Less Common But Serious Side Effects:

• Seizures (rare but significant)
   
• Memory problems or confusion
   
• Mood changes or anxiety
   
• Headaches
   
• Risk of heart issues in vulnerable patients

Tab Enzalutamide 160 mg Price in India

The tab enzalutamide 160 mg price in India varies depending on the brand, manufacturer, and location.

Approximate Price Range:

• ₹20,000 to ₹35,000 for a monthly supply (30 tablets)

Generic versions are now available in India, making it more affordable for patients without compromising on quality. Leading Indian pharmaceutical companies like Steris Healthcare, Cipla, Zydus, and Sun Pharma offer WHO-GMP-certified Enzalutamide formulations. 

Drug Interactions and Precautions

Before beginning Enzalutamide, notify your doctor about all of the drugs and supplements you are taking, particularly:

Warfarin and other blood thinners

Anti-epileptic medications

Antifungal drugs (such as ketoconazole)

HIV protease inhibitors

Immunosuppressants

General Precautions: Use with caution in individuals with severe liver disease. Adjust dosage accordingly.

It is not suggested for use during pregnancy or in women because it is a cancer treatment for males exclusively.

Exercise caution in patients with a history of seizures.

Regularly monitor your blood pressure and liver enzymes.

Why Choose Enzalutamide 160 mg Tablet From Steris Healthcare Pvt Ltd. 

Steris Healthcare Pvt Ltd. is a trusted name in the Indian pharmaceutical industry, known for offering high-quality and clinically proven medications across a wide range of therapeutic segments. When it comes to advanced cancer care, our Enzalutamide 160 mg tablet stands out as a reliable and effective choice for patients battling metastatic castration-resistant prostate cancer (mCRPC) and other advanced forms of prostate cancer.

Our Enzalutamide 160 mg tablet is formulated in WHO-GMP-certified manufacturing units, ensuring consistent quality, purity, and efficacy in every dose. The active ingredient, Enzalutamide, is a second-generation androgen receptor inhibitor that works by blocking the action of male hormones (androgens) that fuel the growth of prostate cancer cells. It is clinically validated to help slow disease progression and improve survival outcomes in patients who may or may not have received prior chemotherapy.

Frequently Asked Questions (FAQs)

Q1. Is Enzalutamide 160 mg a form of chemotherapy?

No. It is a targeted oral hormone therapy, not chemotherapy. It works by blocking androgen receptors, not by killing cells directly.

Q2. How long do I need to take Enzalutamide?

Treatment is usually long-term and continues until the disease progresses or unacceptable side effects occur.

Q3. Is Enzalutamide better than Abiraterone?

Both drugs are effective but act differently. Enzalutamide doesn’t require steroid co-administration, unlike Abiraterone. Your doctor will decide based on your medical history and cancer stage.

Q4. Can Enzalutamide be used in earlier stages of prostate cancer?

It is approved for both non-metastatic and metastatic prostate cancer, especially in hormone-resistant forms.