Introduction

Liver health is critical to overall wellness, and in recent years, advanced medications have become available to support individuals suffering from chronic liver conditions such as primary biliary cholangitis (PBC). One such breakthrough medication is OB-COLLAR 5, a powerful formulation containing obeticholic acid 5 mg. Designed to manage and treat liver diseases by improving bile flow and reducing liver inflammation, OB-COLLAR 5 is now widely recommended by hepatologists and gastroenterologists worldwide.

As a prescription medication based on obeticholic acid, it represents a significant advancement in the treatment of chronic liver conditions where bile ducts are damaged over time. This article explores OB-COLLAR 5, including its uses, mechanism of action, dosage guidelines, side effects, and answers to frequently asked questions. Notably, this medicine is also available in 10 mg strength as obeticholic acid tablets 10 mg, providing flexible dosing options depending on the severity of the condition.

About This Medication

OB-COLLAR 5 contains obeticholic acid 5 mg, a semisynthetic bile acid analogue. It works by binding to and activating the farnesoid X receptor (FXR) in the liver and intestines. This activation helps regulate bile acid synthesis and transport, resulting in reduced bile acid accumulation and inflammation, both of which are key contributors to chronic liver disease progression.

Obeticholic acid is especially effective in treating primary biliary cholangitis (PBC), a rare but progressive autoimmune liver condition that damages the bile ducts. The active ingredient, obeticholic acid, has been studied extensively and approved by major regulatory bodies for its hepatoprotective properties.

Tablet Uses – OB-COLLAR 5

OB-COLLAR 5 is primarily prescribed for:

• Treatment of primary biliary cholangitis (PBC) in adults.

• Used either as monotherapy or in combination with ursodeoxycholic acid (UDCA) in patients who show an inadequate response to UDCA alone.

• Patients intolerant to UDCA may also benefit from obeticholic acid tablets.

These obeticholic acid tablets help in reducing alkaline phosphatase (ALP) levels, an enzyme associated with liver inflammation. Elevated ALP levels are often seen in liver diseases, and reducing them is considered a marker of effective treatment.

Dosage of OB-COLLAR 5

The dosage of OB-COLLAR 5 should be determined by a healthcare provider based on individual liver function and patient response. The general dosing guidelines are as follows:

• Starting dose: One obeticholic acid 5 mg tablet once daily.

• If well-tolerated and additional reduction in ALP is needed, the dose may be increased to 10 mg once daily after 3 to 6 months of therapy.

For patients with moderate to severe hepatic impairment, the dose may be adjusted accordingly to minimize the risk of side effects.

Always take OB-COLLAR 5 exactly as prescribed by your healthcare provider. Do not increase or decrease the dose without consulting your doctor.

What Are the Possible Side Effects of This Medicine?

While OB-COLLAR 5 is effective in managing primary biliary cholangitis, like all medications, it may cause side effects in some individuals. The most commonly reported obeticholic acid side effects include:

Common Side Effects:

• Pruritus (itching) – most frequent and dose-dependent

• Fatigue

• Abdominal pain

• Rash

• Constipation

• Joint pain

Less Common but Serious Side Effects:

• Worsening of liver function in patients with advanced liver disease

• Jaundice (yellowing of skin or eyes)

• Ascites (fluid retention in the abdomen)

• Hepatic decompensation

If you experience any severe reactions or unusual symptoms, stop taking the medication and consult your healthcare provider immediately.

Obeticholic Acid Mechanism of Action

The mechanism of action of obeticholic acid lies in its ability to activate the farnesoid X receptor (FXR). FXR plays a key role in the regulation of bile acid levels in the liver, intestines, and kidneys. By stimulating this receptor, obeticholic acid:

• Suppresses bile acid synthesis in the liver

• Increases bile acid excretion

• Reduces bile acid toxicity

• Decreases liver inflammation and fibrosis

• Improves liver enzyme profiles such as ALP, ALT, and AST

This mechanism makes OB-COLLAR 5 highly effective in delaying disease progression and improving the quality of life for patients with primary biliary cholangitis.

Frequently Asked Questions (FAQs)

What is obeticholic acid?

Obeticholic acid is a bile acid analog used to treat primary biliary cholangitis, an autoimmune liver condition that leads to progressive liver damage. It is the active component in OB-COLLAR 5.

What is obeticholic acid used for?

It is used to manage and treat primary biliary cholangitis in adults who either cannot tolerate ursodeoxycholic acid or do not respond adequately to it.

How does obeticholic acid work?

It works by activating the farnesoid X receptor (FXR), reducing bile acid buildup, decreasing liver inflammation, and improving bile flow, thus helping maintain liver function and reduce disease progression.

How effective is obeticholic acid?

Clinical studies show that obeticholic acid is highly effective in reducing liver enzyme levels such as ALP and improving symptoms of PBC. Many patients experience better liver test results and a reduction in pruritus and fatigue after consistent use.

How much is obeticholic acid?

Prices vary depending on brand, location, and dosage. OB-COLLAR 5 (obeticholic acid 5 mg) is available online at sterisonline, offering competitive pricing for both 5 mg and obeticholic acid tablets 10 mg.

Can obeticholic acid be taken with other medications?

Yes, it can be used in combination with UDCA or other liver medications. However, it's essential to inform your doctor about all medications and supplements you're taking to avoid interactions.

Is OB-COLLAR 5 available in other strengths?

Yes. In addition to the 5 mg strength, it is also available as obeticholic acid tablets 10 mg, suitable for patients requiring a higher dose based on clinical judgment.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it’s close to your next dose, skip the missed one and resume your regular schedule. Do not double the dose.

Storage and Handling

• Store OB-COLLAR 5 at room temperature, away from moisture and direct sunlight.

• Keep it out of reach of children.

• Do not use the medication past its expiry date.

Who Should Not Take OB-COLLAR 5?

OB-COLLAR 5 should be avoided in:

• Patients with complete biliary obstruction

• Individuals with advanced liver disease unless under close monitoring

• Pregnant or breastfeeding women without physician approval

• Anyone allergic to obeticholic acid

Always consult a healthcare provider before beginning therapy.

Why Choose OB-COLLAR 5?

• Contains clinically proven obeticholic acid 5 mg

• Manufactured to high pharmaceutical standards

• Offers relief from chronic liver disease symptoms

• Can be used with other liver medications for synergistic effects

• Available in both 5 mg and 10 mg obeticholic acid tablets

You can buy OB-COLLAR 5 and obeticholic acid tablets 10 mg conveniently from SterisOnline, a trusted platform for authentic medications.

Final Thoughts

Chronic liver conditions like primary biliary cholangitis require long-term care, and OB-COLLAR 5 provides a targeted, effective solution. With its key ingredient obeticholic acid 5 mg, this medication helps restore liver function, reduce inflammation, and slow down disease progression. Patients have reported improved quality of life, reduced fatigue, and better liver test results after starting this therapy.

Whether you're just beginning treatment or looking for a more effective therapy, OB-COLLAR 5 is a reliable option worth discussing with your healthcare provider. And if a higher dose is needed, the obeticholic acid tablets 10 mg variant is also available, giving patients flexibility in managing their condition.

For genuine products and competitive pricing, buy OB-COLLAR 5 and 10 mg online from SterisOnline today and take a proactive step toward liver health and recovery.

About The Company

Steris Healthcare Pvt Ltd, widely recognized as Sterispharma, was established in February 2018 by a team of seasoned experts from the pharmaceutical sector. Based in Navi Mumbai, the company is proudly certified by WHO, GMP, and ISO, underscoring its unwavering commitment to quality and patient safety. Sterispharma is driven by a mission to make affordable, premium-quality medicines accessible throughout India, adhering strictly to WHO-recommended standards. Through its user-friendly online pharmacy platforms, customers can effortlessly order medications with home delivery services.

Sterispharma boasts an extensive portfolio of healthcare solutions, ranging from treatments for rare diseases to essential everyday healthcare needs. Their comprehensive product lineup addresses multiple therapeutic areas including Cardiology, Asthma, Respiratory Disorders, Nasal Care, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infective/Antibiotic Therapy, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medications are easily available for online purchase through their official websites — Sterisonline, Sterisindia, and Sterispharma — offering a seamless and reliable healthcare experience.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

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