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Acamprosate Gastro-resistant 666 mg: Uses, Dosage, Side Effects & Benefits

Sep 04, 2025

Introduction

Alcohol dependence is a serious medical and social condition affecting millions worldwide. Long-term alcohol consumption alters brain chemistry, causing cravings, withdrawal symptoms, anxiety, and a high risk of relapse.ACAMPURE 666 (Acamprosate Gastro-resistant Tablets 666 mg) is a scientifically formulated medication that supports recovery by reducing alcohol cravings and helping patients maintain long-term abstinence. Its gastro-resistant formulation ensures maximum absorption and efficacy, even in patients with sensitive stomachs.

Composition

Each ACAMPURE 666 tablet contains:

  • Acamprosate Calcium – 666 mg (Gastro-resistant)

Excipients: Pharmaceutical-grade stabilizers, binders, and fillers to ensure optimal bioavailability and patient safety.

Pharmacological Action

Chronic alcohol use disrupts the balance of neurotransmitters in the brain:

  • Excess glutamate (excitatory neurotransmitter) – causing cravings and anxiety

  • Reduced GABA (inhibitory neurotransmitter) – leading to nervousness and hyperactivity

Mechanism of Action of Acamprosate:

  1. Glutamate Modulation: Reduces excitatory neurotransmission to calm the brain.

  2. GABAergic Enhancement: Increases inhibitory signaling, promoting relaxation and emotional stability.

  3. Neurochemical Balance Restoration: Supports brain adaptation to life without alcohol, lowering relapse risk.

Clinical Benefits of ACAMPURE 666

  • Reduces Alcohol Cravings: Makes abstinence more manageable.

  • Prevents Relapse: Supports long-term recovery programs.

  • Non-addictive: Safe for continuous therapy.

  • Liver-friendly: Safe in mild to moderate liver impairment.

  • Supports Rehabilitation: Enhances outcomes when combined with therapy and counseling.

  • Improves Mental Well-being: Reduces anxiety, irritability, and withdrawal-related discomfort.

Uses of ACAMPURE 666

ACAMPURE 666 is indicated for:

  • Management of alcohol dependence

  • Prevention of relapse in detoxified patients

  • Reduction of alcohol cravings and urges

  • Support in rehabilitation programs

  • Long-term abstinence maintenance

 Note: This medicine does not treat acute alcohol withdrawal symptoms, which require immediate medical attention.

Dosage and Administration

  • Standard Dose for Adults: 2 tablets (666 mg each) three times daily, preferably after meals.

  • Elderly or low-weight patients: Dose adjustment may be necessary.

  • Mode of Administration: Swallow tablets whole with water; do not crush or chew.

  • Duration of Therapy: Usually 6–12 months, depending on clinical response.

Consistency in dosing is critical for the medication’s efficacy.

Side Effects

Most patients tolerate ACAMPURE 666 well. Possible side effects include:

  • Gastrointestinal: Diarrhea, abdominal discomfort, nausea

  • Nervous system: Headache, dizziness, insomnia

  • Skin: Rash, itching (rare)

  • Others: Fatigue, mild muscle weakness

Most side effects are mild and temporary, and do not require discontinuation.

Precautions and Warnings

  • Kidney Impairment: Contraindicated in severe renal insufficiency.

  • Pregnancy & Breastfeeding: Use only under physician supervision.

  • Children & Adolescents (<18 years): Not recommended.

  • Compliance: Essential for effectiveness; skipping doses reduces benefit.

  • Alcohol Consumption: Avoid completely during treatment.

Drug Interactions

  • Minimal interactions due to renal excretion.

  • Can be safely combined with naltrexone or disulfiram under medical supervision.

  • Alcohol consumption reduces efficacy and increases relapse risk.

Lifestyle and Patient Guidance

  • Behavioral Therapy: Combine medication with counseling, support groups, or cognitive-behavioral therapy.

  • Avoid Triggers: Stay away from social or environmental cues linked to alcohol consumption.

  • Healthy Habits: Balanced diet, adequate hydration, and regular exercise support recovery.

  • Monitoring: Regular follow-ups with your physician to track progress and adjust therapy.

  • Patience: Results improve over weeks; early adherence is key to success.

Why Choose Steris Healthcare Pvt Ltd?

Steris Healthcare is a reliable and ethical pharmaceutical provider offering:

  • WHO-GMP certified manufacturing for premium quality.

  • Clinically proven formulations for safety and effectiveness.

  • Affordable pricing to ensure patient accessibility.

  • Pan-India distribution for easy availability.

  • Trusted brand reputation among healthcare professionals and patients.

By choosing ACAMPURE 666 from Steris Healthcare, patients receive safe, high-quality, and reliable medicine supporting their journey to recovery.

FAQs on ACAMPURE 666

Q1. What is ACAMPURE 666 used for?
It helps reduce alcohol cravings and maintain abstinence in alcohol-dependent patients.

Q2. Can ACAMPURE 666 treat alcohol withdrawal symptoms?
No, it is not for acute withdrawal. Detoxification should be completed before starting this therapy.

Q3. How long should the treatment continue?
Typically 6–12 months, depending on the patient’s clinical response.

Q4. Is ACAMPURE 666 addictive?
No, it is non-habit forming and safe for long-term use.

Q5. Can it be taken with food?
Yes, preferably after meals to reduce stomach irritation and improve absorption.

Q6. Can ACAMPURE 666 be combined with other medications?
Yes, it can be used alongside naltrexone or disulfiram under medical guidance.

Q7. How soon does it work?
Craving reduction may be noticeable after 1–2 weeks, with maximum effect over several weeks.

Q8. Is ACAMPURE 666 safe for patients with liver problems?
Yes, it is generally safe in mild to moderate liver impairment.

Q9. Can I drink alcohol while taking ACAMPURE 666?
No, alcohol intake should be completely avoided for effective therapy.

Q10. Can the therapy be stopped suddenly?
Yes, but consult your doctor before discontinuing to ensure proper follow-up care.

Conclusion

ACAMPURE 666 (Acamprosate Gastro-resistant Tablets 666 mg) is a clinically proven, safe, and effective medication for alcohol dependence. It helps reduce cravings, prevent relapse, and support long-term recovery.When paired with behavioral therapy and lifestyle changes, it becomes a cornerstone of comprehensive alcohol dependence treatment.

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