Terbinafine and itraconazole Tablets uses, dosage, side effects and benefits
Dec 16, 2025
Introduction
In India, fungal infections of the skin and nails are becoming more prevalent because of the country's humid climate, heavy perspiration, and extended usage of occlusive shoes. If left untreated, ailments including ringworm, athlete's foot, jock itch, and fungal nail infections may become chronic and recurring. CONARIS T200 is a potent oral antifungal drug that combines terbinafine and itraconazole to treat moderate to severe fungal infections thoroughly and permanently.
CONARIS T200, which is produced in accordance with strict pharmaceutical quality standards, targets fungi at various phases of their life cycle. Dermatologists favor it for difficult fungal infections because of its dual-action mechanism, which promotes deeper fungal clearance, quicker symptom alleviation, and a lower risk of recurrence.
Uses of CONARIS T200
CONARIS T200 is primarily prescribed for the treatment of various fungal and dermatophytic infections that do not respond adequately to single-drug therapy.
Key uses include:
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Treatment of tinea infections such as tinea corporis (ringworm), tinea cruris (jock itch), and tinea pedis (athlete’s foot)
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Management of onychomycosis (fungal nail infections of fingers and toes)
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Treatment of chronic and recurrent cutaneous fungal infections
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Management of extensive fungal infections involving multiple body areas
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Use in patients with azole-resistant or partially responsive fungal infections
This combination therapy is especially useful in infections where fungi have penetrated deeper layers of skin or nails.
Benefits of Terbinafine 250mg and Itraconazole 200mg Combination
CONARIS T200 offers multiple therapeutic benefits due to its synergistic antifungal action.
Dual Mechanism of Action
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Terbinafine inhibits the enzyme squalene epoxidase, leading to fungal cell death
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Itraconazole disrupts fungal cell membrane synthesis by inhibiting ergosterol production
Together, they provide broader antifungal coverage.
Faster and More Effective Results
The combination helps achieve quicker symptom relief such as itching, redness, scaling, and discomfort while ensuring deeper eradication of fungal infection.
Reduced Risk of Recurrence
By targeting fungi through different pathways, CONARIS T200 lowers the risk of relapse, which is common with monotherapy.
Effective for Nail and Skin Infections
Itraconazole’s tissue penetration and Terbinafine’s fungicidal action make this combination particularly effective for stubborn nail infections.
Convenient Oral Therapy
Oral administration ensures better compliance compared to prolonged topical treatments in extensive infections.
Dosage
The dosage of CONARIS T200 should always be taken as prescribed by a qualified healthcare professional.
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Usually taken once daily or as advised by the doctor
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Tablets should be swallowed whole with water
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Can be taken after food to reduce gastric discomfort
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Duration of treatment may vary from 2 to 6 weeks for skin infections and several weeks to months for nail infections
Patients are advised to complete the full course even if symptoms improve early, as incomplete treatment may lead to recurrence.
Side Effects
Like all medicines, CONARIS T200 may cause side effects, though not everyone experiences them.
Common Side Effects
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Nausea or vomiting
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Abdominal pain or indigestion
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Headache
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Mild skin rash
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Altered taste sensation
Less Common but Serious Side Effects
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Liver enzyme elevation
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Fatigue or weakness
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Dark-colored urine
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Yellowing of skin or eyes (jaundice)
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Severe skin reactions (rare)
Patients experiencing persistent or severe side effects should seek medical attention immediately.
Precautions and Warning
Before starting CONARIS T200, certain precautions must be considered to ensure safe use.
Liver Health
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Not recommended for patients with active or chronic liver disease
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Liver function tests may be advised before and during treatment
Heart Conditions
Itraconazole should be used cautiously in patients with heart-related disorders.
Pregnancy and Breastfeeding
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Not recommended during pregnancy unless clearly advised by a doctor
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Breastfeeding mothers should consult a healthcare professional before use
Drug Interactions
CONARIS T200 may interact with medicines such as:
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Certain heart medications
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Blood thinners
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Antiepileptic drugs
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Some antibiotics
Always inform your doctor about ongoing medications.
Alcohol Consumption
Alcohol should be avoided as it may increase the risk of liver-related side effects.
Frequently Asked Questions (F&Q)
What is CONARIS T200 used for?
CONARIS T200 is used to treat moderate to severe fungal skin and nail infections, especially those that are recurrent or resistant to single antifungal drugs.
How long does CONARIS T200 take to work?
Symptom relief may start within a few days, but complete fungal clearance may take several weeks depending on the severity and type of infection.
Can CONARIS T200 be taken for nail fungus?
Yes, this combination is highly effective for fungal nail infections due to its deep tissue penetration.
Is CONARIS T200 safe for long-term use?
Long-term use should only be done under medical supervision with regular liver function monitoring.
Can I stop taking CONARIS T200 once itching reduces?
No, stopping treatment early can lead to recurrence. Always complete the prescribed course.
Conclusion
Terbinafine 250mg and Itraconazole 200mg Tablets is a clinically effective solution for managing stubborn, recurrent, and deep-seated fungal infections. Its dual-action antifungal mechanism ensures faster relief, broader coverage, and reduced chances of relapse, making it a reliable option for dermatological fungal conditions.
With proper medical guidance, adherence to dosage, and necessary precautions, CONARIS T200 can significantly improve patient outcomes and quality of life. For individuals struggling with persistent fungal infections, this combination therapy offers a trusted and comprehensive treatment approach.
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