Introduction

Diabetes mellitus, especially Type 2 Diabetes (T2DM), is one of the most common chronic conditions worldwide. Managing blood glucose effectively is crucial to preventing complications such as kidney failure, nerve damage, cardiovascular disease, and vision problems. GLISITAPTIN M 1000 is a trusted antidiabetic medicine that combines two powerful agents – Sitagliptin Phosphate and Metformin Hydrochloride – to provide comprehensive glycemic control.

Composition

• Sitagliptin Phosphate

• Metformin Hydrochloride (1000 mg)

This dual-combination therapy works synergistically to improve blood sugar control in adults with Type 2 Diabetes Mellitus (T2DM).

How GLISITAPTIN M 1000 Works (Mechanism of Action)

1. Sitagliptin Phosphate (DPP-4 Inhibitor):

   • Enhances the body’s natural ability to lower blood sugar.

   • Increases incretin hormone levels, which stimulate insulin release and decrease glucagon secretion.

   • Works in a glucose-dependent manner, reducing the risk of hypoglycemia.

2. Metformin Hydrochloride (Biguanide):

   • Reduces glucose production in the liver.

   • Improves insulin sensitivity and enhances glucose uptake in muscles.

   • Helps reduce intestinal absorption of glucose.

Together, this combination offers dual benefits – targeting insulin secretion as well as insulin sensitivity.

Uses of Sitagliptin Phosphate & Metformin Hydrochloride Tablets

GLISITAPTIN M 1000 is primarily prescribed for:

• Type 2 Diabetes Mellitus (T2DM): Helps control high blood sugar levels.

• Prevention of Diabetes Complications: Reduces the risk of kidney problems, heart disease, nerve damage, and vision issues.

• Weight & Metabolic Benefits: May support modest weight control when combined with diet and exercise.

Key Benefits

•  Effective dual therapy for diabetes management.
•  Reduces fasting and postprandial (after meal) blood sugar.
•  Low risk of hypoglycemia compared to some other antidiabetic drugs.
•  Helps improve HbA1c levels significantly.
•  Enhances insulin response naturally without overstimulation.

Dosage & Administration

• Recommended dose: As prescribed by a doctor.

• Usually taken once or twice daily with meals to minimize gastrointestinal side effects.

• Dosage depends on blood sugar levels, age, and medical history.
   Never self-adjust the dosage without medical supervision.

Side Effects of Sitagliptin Phosphate & Metformin Hydrochloride Tablets

While generally well tolerated, some patients may experience:

• Common Side Effects:

  • Nausea, vomiting, or stomach upset

  • Diarrhea

  • Headache

  • Mild hypoglycemia (rare)

• Serious but Rare Side Effects:

  • Lactic acidosis (a serious condition linked to Metformin)

  • Severe allergic reaction

  • Pancreatitis (in rare cases with Sitagliptin)

Seek medical advice immediately if you notice severe abdominal pain, unusual muscle pain, or breathing difficulty.

Precautions & Warnings

• Not recommended for Type 1 Diabetes or Diabetic Ketoacidosis (DKA).

• Use with caution in patients with kidney or liver problems.

• Pregnant and breastfeeding women should consult their doctor before use.

• Avoid alcohol as it increases the risk of lactic acidosis.

Drug Interactions

• May interact with insulin or other oral antidiabetics, increasing the risk of hypoglycemia.

• Certain drugs like diuretics, steroids, and heart medications may affect its effectiveness.

• Always inform your doctor about your ongoing medications.

Price of Sitagliptin Phosphate & Metformin Hydrochloride Tablets in India

The price of GLISITAPTIN M 1000 may vary depending on brand, region, and pack size. Steris Healthcare ensures affordable pricing without compromising on quality.

Why Choose GLISITAPTIN M 1000 from Steris Healthcare Pvt Ltd?

• Trusted Pharmaceutical Brand: Known for quality and affordability.

• WHO-GMP Certified Manufacturing: Ensures safety and efficacy.

• Patient-Centric Approach: Focused on improving treatment outcomes.

• Pan-India Availability: Easily accessible across different regions.

• Affordable & Reliable: High-quality medicine at competitive prices.

FAQs about Sitagliptin Phosphate & Metformin Hydrochloride Tablets

Q1. What is GLISITAPTIN M 1000 used for?
GLISITAPTIN M 1000 is used to treat Type 2 Diabetes Mellitus by lowering high blood sugar levels and preventing long-term complications.

Q2. How should I take Sitagliptin & Metformin tablets?
It should be taken with meals, usually once or twice daily, as prescribed by your doctor.

Q3. Can GLISITAPTIN M 1000 cause hypoglycemia?
Alone, it has a low risk of hypoglycemia, but if combined with insulin or sulfonylureas, the risk may increase.

Q4. Is this tablet safe for kidney patients?
Caution is required. Patients with kidney problems should only take this medicine under strict medical supervision.

Q5. What should I avoid while taking Sitagliptin & Metformin?
Avoid alcohol as it increases the risk of lactic acidosis. Always follow your doctor’s advice on diet and lifestyle.

Q6. Can pregnant women take GLISITAPTIN M 1000?
It should be taken during pregnancy or breastfeeding only if prescribed by a doctor.

Conclusion

GLISITAPTIN M 1000 (Sitagliptin Phosphate & Metformin Hydrochloride Tablets) is a powerful and effective treatment option for Type 2 Diabetes Mellitus, offering better blood sugar control with minimal risk of hypoglycemia. By combining the benefits of Sitagliptin and Metformin, it helps patients achieve long-term glycemic control, prevents complications, and supports overall well-being. For safe, effective, and affordable treatment, Steris Healthcare Pvt Ltd is your trusted choice for GLISITAPTIN M 1000.