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Sacubitril and Valsartan Tablets: Uses, Dosage, Side Effects & Price

Sep 09, 2025

Introduction to Sacubitril and Valsartan Tablets

Sacubitril and Valsartan tablets are a combination medicine widely prescribed for the treatment of chronic heart failure. The formulation helps reduce the strain on the heart and improves overall cardiac function. Marketed under the brand name SACUBRIGHT 200, this medication contains Sacubitril 97 mg and Valsartan 103 mg, together forming a 200 mg tablet.

It is clinically proven to improve survival rates, reduce hospitalizations, and enhance the quality of life in patients with heart failure.

What is Sacubitril and Valsartan?

  • Sacubitril and Valsartan belong to a class of drugs called angiotensin receptor neprilysin inhibitors (ARNIs).

  • Sacubitril works by blocking neprilysin, an enzyme that breaks down heart-protective peptides, thereby relaxing blood vessels and reducing stress on the heart.

  • Valsartan is an angiotensin II receptor blocker (ARB) that lowers blood pressure and prevents narrowing of blood vessels.

Together, they provide a powerful synergistic effect in treating heart failure with reduced ejection fraction (HFrEF).

Sacubitril and Valsartan Tablet Uses

The main uses of sacubitril and valsartan tablets include:

  • Treatment of chronic heart failure in adults

  • Reducing the risk of hospitalization due to heart failure

  • Improving survival in heart failure patients

  • Managing high blood pressure in some cases

Sacubitril Valsartan Tablets Uses in Heart Failure

Sacubitril valsartan tablets uses are primarily in heart failure management. Studies show that patients taking Sacubitril valsartan 200 mg have significantly better outcomes compared to traditional ACE inhibitors.

Sacubitril Valsartan Mechanism of Action

The sacubitril valsartan mechanism of action works on two pathways:

  1. Sacubitril inhibits neprilysin, increasing levels of natriuretic peptides that dilate blood vessels and decrease fluid overload.

  2. Valsartan blocks angiotensin II receptors, lowering blood pressure and reducing strain on the heart.

This dual mechanism reduces stress on the heart, improves cardiac efficiency, and prevents further complications.

Sacubitril Valsartan 200 mg Tablet (SACUBRIGHT 200)

  • Brand Name: SACUBRIGHT 200

  • Composition: Sacubitril 97 mg + Valsartan 103 mg

  • Strength: 200 mg tablet

  • Packaging: Available in strips or blister packs as prescribed

Sacubitril Valsartan 200 mg Price

The sacubitril valsartan 200 mg price may vary depending on the manufacturer and location. On average, the cost is affordable compared to international brands, making it accessible for long-term treatment. For updated pricing, consult your nearest pharmacy or contact Steris Healthcare Pvt Ltd.

Sacubitril and Valsartan Tablets Dosage

  • The recommended starting dose is usually sacubitril valsartan 50–100 mg twice daily, gradually increased to 200 mg twice daily, based on patient tolerance.

  • Tab sacubitril valsartan 200 mg is typically used for patients who are stabilized and require a full-strength dose.

  • Always follow your doctor’s prescription for correct dosage and duration.

Sacubitril and Valsartan Tablets Side Effects

Like all medicines, sacubitril and valsartan tablets may cause side effects. Common ones include:

  • Low blood pressure (hypotension)

  • Dizziness or lightheadedness

  • Increased potassium levels

  • Kidney function changes

  • Cough or fatigue

Serious side effects may include angioedema (swelling of face, lips, or throat). Patients must seek immediate medical help if this occurs.

Why Choose SACUBRIGHT 200 from Steris Healthcare Pvt Ltd?

  • Manufactured under WHO-GMP certified facilities

  • Ensures highest quality standards and efficacy

  • Affordable pricing compared to multinational brands

  • Backed by Steris Healthcare’s trusted pharma expertise

  • Available with nationwide distribution network

Steris Healthcare is committed to providing affordable, effective, and safe medicines to patients across India.

FAQs on Sacubitril and Valsartan Tablets

Q1. What are the main uses of sacubitril and valsartan tablets?

They are mainly used to treat chronic heart failure and to reduce the risk of hospitalization and mortality.

Q2. What is the sacubitril valsartan mechanism of action?

It works by inhibiting neprilysin (Sacubitril) and blocking angiotensin II receptors (Valsartan) to improve heart function.

Q3. What is the price of sacubitril valsartan 200 mg in India?

The sacubitril valsartan 200 mg price varies, but SACUBRIGHT 200 from Steris Healthcare is available at an affordable cost.

Q4. Can sacubitril valsartan tablets be used during pregnancy?

No, these tablets are not recommended during pregnancy. Always consult your doctor.

Q5. What are the side effects of sacubitril valsartan tablets?

Common side effects include low blood pressure, dizziness, high potassium, and kidney function changes.

Conclusion

Sacubitril and Valsartan tablets (SACUBRIGHT 200) are an advanced treatment option for chronic heart failure. With proven benefits in reducing hospitalization and improving patient survival, they represent a breakthrough in cardiac care. Manufactured by Steris Healthcare Pvt Ltd, this medicine is safe, effective, and affordable.If you are searching for sacubitril valsartan 200 mg tablets, choose SACUBRIGHT 200 from Steris Healthcare for trusted quality and better health outcomes.

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