Obeticholic Acid 10 mg tablet is a prescription medication used in the treatment of chronic liver conditions, particularly Primary Biliary Cholangitis (PBC)—a progressive autoimmune disease that affects the liver’s bile ducts. This medicine belongs to the class of drugs called Farnesoid X Receptor (FXR) agonists, which play an essential role in regulating bile acid synthesis and secretion within the liver and intestines.

Over time, Obeticholic Acid 10 mg has become a key therapeutic option for individuals who do not achieve adequate results from first-line treatment like Ursodeoxycholic Acid (UDCA). In this guide, we will explore in-depth its uses, benefits, dosage, side effects, and important precautions. 

What is Obeticholic Acid 10 mg?

Obeticholic Acid 10 mg Tablet is a synthetic bile acid derivative that targets and activates FXR receptors. These receptors help control how bile acids are produced and transported in the liver. When activated, FXR receptors reduce the toxic accumulation of bile acids, thus protecting liver cells from damage—a common problem in PBC and other cholestatic liver diseases.

This drug is FDA-approved for use along with UDCA in patients who have an insufficient response to it or as a standalone treatment in individuals who cannot tolerate UDCA. 

Uses of Obeticholic Acid (10 mg) 

Both patients and caregivers should be aware of the precise applications for Obeticholic Acid 10 mg. Its main medicinal uses are as follows:

1. Primary Biliary Cholangitis (PBC) treatment
PBC is the main indication for this drug. This disorder causes inflammation, bile accumulation, and ultimately liver scarring by gradually destroying the liver's bile ducts. By decreasing bile acid toxicity and delaying the course of the illness, obeeticholic acid aids in its management. 

2. Improving the Function of the Liver
This drug suppresses bile acid synthesis through FXR activation, which restores equilibrium and may be very beneficial for patients with reduced liver function brought on by excess bile acid.

3. Being looked into for NASH 
Obeticholic Acid 10 mg is being investigated in clinical studies for Non-Alcoholic Steatohepatitis (NASH), a more severe form of fatty liver disease, even though it is not yet licensed for this usage. 

How Obeticholic Acid 10 mg Tablet Works

The therapeutic effect of this tablet comes from its activation of the Farnesoid X Receptor (FXR), which is involved in maintaining bile acid homeostasis.

Once activated, FXR:

• Reduces bile acid production in the liver

• Increases bile acid clearance and secretion

• Minimizes inflammation and fibrosis (scarring)

• Aids in regulating cholesterol and glucose metabolism

This multi-mechanism approach plays a critical role in protecting liver cells and preventing long-term complications such as cirrhosis and liver failure.

Key Benefits of Obeticholic Acid 10 mg Tablet

Patients using Obeticholic Acid 10 mg often experience significant improvement, especially those not responding well to traditional treatments. Key benefits include:

• Improves Liver Enzymes
  Notably reduces ALP (Alkaline Phosphatase)—a marker for liver inflammation in PBC patients.

• Delays Liver Disease Progression
  Helps slow fibrosis and reduces the likelihood of liver failure or cirrhosis.

• Effective Alternative for UDCA-Intolerant Patients
  Offers a safe and effective option when UDCA cannot be used.

• Improves Quality of Life
  Alleviates symptoms like fatigue and itching, enhancing daily functioning.

• Convenient Once-Daily Dosing
  A simplified regimen promotes better adherence and treatment continuity.  

Side Effects of Obeticholic Acid 10 mg Tablet

While generally well-tolerated, some individuals may experience side effects when using Obeticholic Acid 10 mg. These can vary in intensity.

Common Side Effects:

Itching (Pruritus) – most frequently reported

Fatigue

Abdominal pain

Nausea

Joint discomfort

Less Common Side Effects:

Skin rashes or irritation

Constipation or diarrhea

Dizziness

Swelling in the legs or ankles

Serious but Rare Side Effects:

Worsening liver function, especially in patients with cirrhosis

Liver decompensation

Hospitalization due to liver complications

If you notice any unusual symptoms, it is crucial to consult your healthcare provider immediately. Routine liver function tests are important during therapy.

Why Choose Steris Healthcare for Tablets of Obeticholic Acid (10 mg)?

Steris Healthcare is a name that is connected with clinical expertise, quality, and confidence in liver care. Steris Healthcare's Obeticholic Acid 10 mg Tablet is produced strictly in accordance with WHO-GMP-certified quality standards, guaranteeing that each dosage provides reliable results and safety. 

Steris Healthcare minimizes possible adverse effects while optimizing treatment efficacy by crafting this liver care solution with good bioavailability and tolerability in mind. For individuals with chronic liver illnesses like PBC, where long-term treatment is necessary, this makes it perfect.

Steris Healthcare's patient-first concept is what really makes it stand out. Every stage, from creation to distribution, is optimized for price, accessibility, and efficacy. Steris is a top option for patients and healthcare professionals in India because of its clear labeling, prompt assistance, and reputation as a clinician-trusted product.