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Nitroglycerine SR 6.4 mg

Jun 30, 2022

Nitroglycerin SR 6.4 mg, a well-known nitrate, is present in NITROQUICK 6.4, a sustained-release cardiovascular medication intended to prevent and treat angina pectoris (chest discomfort linked to coronary artery disease). For many years, nitroglycerin has been a mainstay in cardiology because of its quick and dependable vasodilatory effect, which increases blood flow to the heart muscle.

Angina happens when the heart muscle does not get enough blood that is rich in oxygen, frequently as a result of coronary artery constriction. NITROQUICK 6.4 improves oxygen supply and lessens the burden on the heart by relaxing and expanding blood vessels. Because the sustained-release formulation guarantees a long-lasting therapeutic impact, it is more appropriate for ongoing angina prevention than for immediate treatment.

With increasing incidence of ischemic heart disease in India, NITROQUICK 6.4 offers a dependable option for long-term angina control, helping patients maintain functional capacity and quality of life.

Uses

NITROQUICK 6.4 is prescribed for cardiovascular conditions where long-acting nitrate therapy is required:

1. Prevention of Angina Pectoris

The primary use of NITROQUICK 6.4 is the prevention of chronic stable angina. Regular use reduces the frequency and severity of chest pain episodes.

2. Coronary Artery Disease (CAD)

It is widely used in patients with coronary artery disease to improve myocardial oxygen supply and reduce ischemic symptoms.

3. Adjunct Therapy in Ischemic Heart Conditions

NITROQUICK 6.4 may be used along with beta-blockers, calcium channel blockers, antiplatelets, or statins for comprehensive cardiac care.

4. Post-Myocardial Infarction Management

In selected patients, long-acting nitrates help reduce cardiac workload during recovery and long-term management after heart attack, as advised by a cardiologist.

Benefits

NITROQUICK 6.4 offers multiple clinical and patient-centric advantages:

1. Sustained Angina Prevention

The SR formulation provides prolonged nitrate action, ensuring round-the-clock protection against angina episodes.

2. Reduces Cardiac Workload

By dilating veins and arteries, Nitroglycerin decreases preload and afterload, significantly reducing stress on the heart.

3. Improves Exercise Tolerance

Patients experience fewer angina attacks during physical activity, allowing better daily functioning and mobility.

4. Enhances Coronary Blood Flow

Improved blood supply to the heart muscle reduces ischemia and helps prevent chest pain.

5. Proven and Trusted Therapy

Nitroglycerin is one of the most extensively studied anti-anginal agents, with well-established efficacy and safety.

6. Suitable for Long-Term Use

When used as prescribed with nitrate-free intervals, NITROQUICK 6.4 is appropriate for long-term angina management.

Dosage

The dosage of NITROQUICK 6.4 should be individualized based on the patient’s clinical condition and physician’s judgment.

General Dosage Guidelines:

  • Usual Dose: One tablet once or twice daily, as prescribed

  • Route: Oral

  • Administration: Tablets should be swallowed whole with water; do not crush or chew

Important Dosage Considerations:

  • A nitrate-free interval is essential to prevent tolerance

  • Dose adjustments may be required based on response and side effects

  • Elderly patients may require lower initial doses

Patients should follow the prescribed schedule strictly and should not modify the dose without consulting their doctor.

Side Effects

NITROQUICK 6.4 is generally well tolerated, especially when therapy is initiated gradually. However, some side effects may occur.

Common Side Effects:

  • Headache (most common, usually transient)

  • Dizziness or lightheadedness

  • Flushing

  • Mild nausea

Less Common Side Effects:

  • Low blood pressure

  • Palpitations

  • Fatigue

Rare but Serious Side Effects:

  • Severe hypotension

  • Fainting

  • Allergic reactions

Most headaches reduce with continued use. Persistent or severe symptoms should be reported to a healthcare professional.

Precautions and Warning

Certain precautions must be observed to ensure safe use of NITROQUICK 6.4:

1. Hypotension Risk

Use with caution in patients prone to low blood pressure, dehydration, or volume depletion.

2. Drug Interactions

NITROQUICK 6.4 should not be used with phosphodiesterase-5 inhibitors (such as sildenafil or tadalafil), as this can cause severe hypotension.

3. Tolerance Development

Continuous nitrate exposure may reduce effectiveness. Proper dosing schedules with nitrate-free intervals are essential.

4. Heart Conditions

Patients with hypertrophic cardiomyopathy or severe anemia should use nitrates only under specialist supervision.

5. Pregnancy and Breastfeeding

Use only if clearly prescribed by a healthcare professional after assessing benefits and risks.

6. Alcohol Use

Alcohol can enhance the blood pressure-lowering effect and should be avoided or limited.

Conclusion

NITROQUICK 6.4, containing Nitroglycerin SR 6.4 mg, is a reliable and clinically proven therapy for the long-term prevention of angina pectoris. Its sustained-release formulation ensures prolonged vasodilation, reduced cardiac workload, and improved myocardial oxygen delivery, making it a valuable component of comprehensive cardiovascular care.

With its established efficacy, predictable pharmacological action, and suitability for chronic use, NITROQUICK 6.4 remains a trusted choice for healthcare professionals managing patients with coronary artery disease and chronic angina. When used appropriately under medical supervision, it significantly improves symptom control, functional capacity, and overall quality of life.

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