Introduction

NINTEPRIDE 150 contains Nintedanib 150 mg in soft gelatin capsule form and is prescribed for the treatment of idiopathic pulmonary fibrosis (IPF), interstitial lung diseases associated with systemic sclerosis (SSc-ILD), and progressive fibrosing interstitial lung diseases (PF-ILD). Manufactured under stringent quality standards, NINTEPRIDE 150 offers a reliable and effective therapeutic option for patients managing chronic fibrosing lung conditions.

What is Nintedanib 150 mg?

Nintedanib 150 mg is a tyrosine kinase inhibitor (TKI) that blocks multiple pathways involved in the fibrosis and progression of lung diseases. It is primarily used in the management of idiopathic pulmonary fibrosis (IPF) and other fibrosing interstitial lung diseases.Nintedanib works by inhibiting vascular endothelial growth factor receptors (VEGFRs), platelet-derived growth factor receptors (PDGFRs), and fibroblast growth factor receptors (FGFRs) — all of which contribute to the proliferation and migration of fibroblasts, leading to lung tissue scarring.

Brand Name:

NINTEPRIDE 150

Composition:

Each soft gelatin capsule contains:
Nintedanib Esylate equivalent to Nintedanib 150 mg

Dosage Form:

Soft Gelatin Capsules

Therapeutic Class:

Antifibrotic Agent / Tyrosine Kinase Inhibitor (TKI)

Nintedanib 150 mg Uses

NINTEPRIDE 150 is used for:

1. Idiopathic Pulmonary Fibrosis (IPF):
   A chronic, progressive lung disease characterized by scarring (fibrosis) of lung tissue, causing respiratory decline.

2. Systemic Sclerosis-associated Interstitial Lung Disease (SSc-ILD):
   A connective tissue disorder leading to lung fibrosis.

3. Progressive Fibrosing Interstitial Lung Diseases (PF-ILD):
   For patients with interstitial lung diseases showing progressive fibrosis not caused by IPF or SSc.

How Nintedanib 150 mg Works

Nintedanib inhibits:

• VEGFR (1–3): Reduces angiogenesis and inflammation.

• FGFR (1–3): Prevents fibroblast activation.

• PDGFR (α and β): Limits fibroblast proliferation and migration.

These actions slow down the fibrotic process and preserve lung function, offering symptomatic relief and reducing disease progression.

Recommended Dosage and Administration

• Standard Dose: 150 mg twice daily, taken 12 hours apart.

• Administration: Take with food to reduce gastrointestinal side effects.

• Missed Dose: Skip if more than 3 hours late. Do not double the dose.

Always follow the healthcare provider’s instructions.

Side Effects of Nintedanib 150 mg

While effective, nintedanib 150 mg may cause certain side effects. Common and serious side effects include:

Common Side Effects:

• Diarrhea (most common)

• Nausea

• Vomiting

• Decreased appetite

• Abdominal pain

• Elevated liver enzymes

• Headache

Serious Side Effects:

• Liver toxicity

• Arterial thromboembolic events

• Bleeding complications

• Gastrointestinal perforation

Precautions and Warnings

• Hepatic Impairment: Monitor liver function tests regularly.

• Bleeding Risk: Caution in patients with bleeding disorders or on anticoagulants.

• Gastrointestinal Disorders: Increased risk of GI perforation.

• Pregnancy: Contraindicated; may cause fetal harm.

• Breastfeeding: Not recommended during treatment.

Drug Interactions

Avoid co-administration with:

• CYP3A4 inhibitors/inducers (e.g., ketoconazole, rifampin)

• P-glycoprotein inhibitors (e.g., verapamil)

• Anticoagulants (may increase bleeding risk)

Consult your physician before starting any new medication.

Storage Instructions

• Store below 25°C.

• Protect from moisture and light.

• Keep out of reach of children.

FAQs About Nintedanib 150 mg

Q1. What is NINTEPRIDE 150 used for?

NINTEPRIDE 150 is used to treat idiopathic pulmonary fibrosis (IPF), systemic sclerosis-associated interstitial lung disease (SSc-ILD), and progressive fibrosing interstitial lung diseases (PF-ILD).

Q2. How long does it take for Nintedanib 150 mg to show results?

Nintedanib slows disease progression over months. It does not cure IPF but helps reduce lung function decline.

Q3. Can Nintedanib 150 mg cause liver damage?

Yes. Nintedanib may elevate liver enzymes. Routine liver function monitoring is advised.

Q4. Is it safe to take Nintedanib 150 mg during pregnancy?

No. Nintedanib is contraindicated in pregnancy due to risk of fetal harm.

Q5. Can I stop taking NINTEPRIDE 150 suddenly?

No. Consult your doctor before stopping. Sudden discontinuation may worsen symptoms.

Conclusion

NINTEPRIDE 150 (Nintedanib 150 mg Soft Gelatin Capsules) is a powerful antifibrotic therapy that plays a vital role in managing complex lung diseases like IPF and SSc-ILD. With its proven efficacy in slowing disease progression, it offers patients a better chance at maintaining lung function and quality of life. Regular monitoring and adherence to medical advice are key to maximizing benefits while minimizing risks.

About The Company

Steris Healthcare Pvt Ltd, widely recognized as Sterispharma, was established in February 2018 by a team of seasoned experts from the pharmaceutical sector. Based in Navi Mumbai, the company is proudly certified by WHO, GMP, and ISO, underscoring its unwavering commitment to quality and patient safety. Sterispharma is driven by a mission to make affordable, premium-quality medicines accessible throughout India, adhering strictly to WHO-recommended standards. Through its user-friendly online pharmacy platforms, customers can effortlessly order medications with home delivery services.

Sterispharma boasts an extensive portfolio of healthcare solutions, ranging from treatments for rare diseases to essential everyday healthcare needs. Their comprehensive product lineup addresses multiple therapeutic areas including Cardiology, Asthma, Respiratory Disorders, Nasal Care, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infective/Antibiotic Therapy, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medications are easily available for online purchase through their official websites — Sterisonline, Sterisindia, and Sterispharma — offering a seamless and reliable healthcare experience.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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