NINTEDONE 150 is a prescription oral medication containing Nintedanib 150 mg, a targeted therapy primarily used in the treatment of Idiopathic Pulmonary Fibrosis (IPF), Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD), and Non-Small Cell Lung Cancer (NSCLC). Nintedanib belongs to a class of drugs known as tyrosine kinase inhibitors, which work by blocking multiple pathways that lead to tissue scarring (fibrosis) and tumor growth.By slowing down disease progression and reducing lung function decline, Tab Nintedanib 150 mg offers hope and extended quality of life for patients battling progressive lung diseases and certain types of cancers.

What is Nintedanib 150 mg Used For?

Nintedanib 150 mg capsules (NINTEDONE 150) are indicated for the treatment of:

• Idiopathic Pulmonary Fibrosis (IPF) – a progressive, irreversible lung disease characterized by fibrosis (scarring)

• Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD) – a condition where lung tissue becomes inflamed and scarred

• Non-Small Cell Lung Cancer (NSCLC) – particularly advanced stages in combination with docetaxel after chemotherapy failure

Mechanism of Action – How Nintedanib Works

Nintedanib is a multikinase inhibitor that blocks several growth factor receptors involved in fibrosis and tumor growth, including:

• VEGFR (Vascular Endothelial Growth Factor Receptor)

• FGFR (Fibroblast Growth Factor Receptor)

• PDGFR (Platelet-Derived Growth Factor Receptor)

By targeting these receptors, Nintedone 150 reduces inflammation, vascular remodeling, and fibroblast activity—ultimately slowing lung fibrosis and cancer progression.

Benefits of NINTEDONE 150 (Nintedanib 150 mg)

• Slows lung function decline in IPF and SSc-ILD

• Reduces fibrosis-related complications

• Improves progression-free survival in NSCLC

• Oral administration makes it more convenient than infusions

• Backed by robust clinical trials (INPULSIS, SENSCIS, LUME-Lung 1)

Nintedanib 150 mg Dosage

• The typical recommended dose is 150 mg twice daily, approximately 12 hours apart, taken with food.

• Dose adjustments may be necessary for adverse reactions such as liver enzyme elevation or severe diarrhea.

• Always follow the dosage as prescribed by your physician.

Side Effects of Nintedanib 150 mg

Like all potent medications, Cap Nintedanib 150 mg may cause side effects. Common and serious ones include:

Common Side Effects:

• Diarrhea (most frequent)

• Nausea or vomiting

• Abdominal pain

• Loss of appetite

• Headache

• Elevated liver enzymes (ALT, AST)

• Weight loss

Serious Side Effects:

• Liver toxicity

• Gastrointestinal bleeding or perforation

• Arterial thromboembolic events

• Hypertension

• Risk of embryo-fetal toxicity (contraindicated in pregnancy)

Always report severe or persistent side effects to your healthcare provider.

Precautions Before Using NINTEDONE 150

• Regular liver function monitoring is required

• Not recommended during pregnancy or breastfeeding

• Use cautiously in patients with bleeding disorders

• Avoid in those with known hypersensitivity to Nintedanib or soy lecithin

• Maintain adequate hydration to minimize GI side effects

• Do not use concurrently with anticoagulants without supervision

Drug Interactions – What Drugs Interact with Nintedanib?

Some medications can affect the blood levels or effectiveness of Nintedanib. Notable interactions include:

• P-glycoprotein inhibitors/inducers (e.g., ketoconazole, rifampicin)

• Anticoagulants and antiplatelets (e.g., warfarin, aspirin) – increased risk of bleeding

• CYP3A4 inhibitors may slightly alter drug exposure

• Herbal supplements like St. John’s Wort should be avoided

Inform your doctor about all the medications and supplements you are taking.

Nintedanib 150 mg Price in India

The Nintedanib 150 mg price can vary depending on the brand and manufacturer. 

Why Choose NINTEDONE 150 from Steris Healthcare?

NINTEDONE 150, by Steris Healthcare Pvt Ltd, is developed with the utmost precision to meet the therapeutic needs of patients suffering from serious lung conditions like IPF and NSCLC. It is a cost-effective, clinically trusted formulation of Nintedanib 150 mg, available at a much more accessible price than global counterparts.

Here’s why it stands out:

• Manufactured in WHO-GMP, ISO, and GLP-certified facilities

• Ensures bioequivalent performance to international brands like Ofev®

• Contains clinically validated Nintedanib 150 mg with reliable sustained absorption

• Packed in moisture-protective, pharma-grade blister packs to maintain shelf-life

• Affordable pricing without compromising on safety or efficacy

• Supported by Steris Healthcare's wide medical network and national distribution

Whether you're treating idiopathic pulmonary fibrosis, systemic sclerosis-related ILD, or advanced NSCLC, NINTEDONE 150 offers dependable outcomes and enhanced patient compliance.

Frequently Asked Questions (FAQs)

Q1. What is nintedanib 150 mg used for?

Nintedanib 150 mg is used to treat idiopathic pulmonary fibrosis (IPF), systemic sclerosis-associated ILD, and some types of non-small cell lung cancer (NSCLC).

Q2. What are the benefits of nintedanib?

By doing this, persistent fibrotic processes are lessened, and the development of permanent damage is postponed. Nintedanib is prescribed to treat progressive phenotypic interstitial lung disease, systemic sclerosis-associated interstitial lung disease, and idiopathic pulmonary fibrosis.

Q3. How should I take NINTEDONE 150?

Take one capsule of Nintedanib 150 mg twice daily with food, about 12 hours apart. Swallow whole—do not crush or chew.

Q4. Can Nintedanib 150 mg be used long-term?

Yes, in conditions like IPF or SSc-ILD, long-term treatment is often necessary. Regular monitoring by your doctor is required to manage side effects and liver health.

Q5. What are the side effects of Nintedanib 150 mg?

Common side effects include diarrhea, nausea, elevated liver enzymes, and loss of appetite. Rarely, serious liver or GI complications may occur.

Conclusion

NINTEDONE 150 is a breakthrough therapy offering renewed hope for patients battling progressive lung diseases and advanced lung cancer. With its targeted mechanism, oral convenience, and proven clinical efficacy, Nintedanib 150 mg is a cornerstone in modern pulmonary and oncology care. When prescribed responsibly and monitored regularly, it provides significant benefits in slowing disease progression and improving quality of life.