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Empagliflozin and Metformin Hydrochloride Extended Release Tablets.

Jul 17, 2025

Brand Name: Gliempaflozin Met ER
Composition: Empagliflozin + Metformin Hydrochloride Extended Release
Manufacturer: Steris Healthcare Pvt. Ltd.

If you are managing Type 2 Diabetes Mellitus and seeking an effective dual-action treatment, Empagliflozin and Metformin Hydrochloride Extended Release Tablets under the brand Gliempaflozin Met ER by Steris Healthcare present a clinically proven and well-tolerated option. This fixed-dose combination is designed to maintain glycemic control while offering added benefits for cardiovascular and kidney health. Let’s explore its uses, benefits, dosage, pricing, side effects, and more

What is Gliempaflozin Met ER?

Gliempaflozin Met ER is a fixed-dose oral antidiabetic medication that combines:

  • Empagliflozin, an SGLT2 inhibitor that promotes urinary glucose excretion
     
  • Metformin Hydrochloride (Extended Release), a biguanide that improves insulin sensitivity and reduces glucose production
     

This extended-release formula ensures sustained action, reducing the frequency of dosing and improving adherence.
 

Empagliflozin and Metformin Hydrochloride ER Tablet Uses

This combination is primarily prescribed for:

1. Type 2 Diabetes Mellitus

  • Improves glycemic control as an adjunct to diet and exercise
     
  • Helps reduce fasting and post-meal blood glucose levels

2. Cardiovascular Risk Management

  • Empagliflozin has been shown to lower the risk of cardiovascular death in patients with established heart disease
     

3. Chronic Kidney Disease (CKD)

  • Provides renal protection and slows the progression of kidney damage in diabetic patients

 

How Does This Medication Work?

Mechanism of Action

  • Empagliflozin: Inhibits the SGLT2 protein in the kidneys, reducing glucose reabsorption and increasing urinary glucose excretion
  • Metformin ER: Reduces hepatic glucose production, enhances peripheral glucose uptake, and delays glucose absorption in the gut

Together, they offer multi-targeted glycemic control and contribute to reducing long-term diabetes complications.

 

Key Features of Gliempaflozin Met ER by Steris Healthcare

  • Extended-Release Technology: Offers steady blood glucose control throughout the day
     
  • Cardio-Renal Protection: Supports heart and kidney health beyond glucose control
     
  • Dual-Action Formula: Targets different mechanisms for more effective results
     
  • WHO-GMP Certified Manufacturing: Ensures international-quality standards
     
  • Reliable & Affordable: From the trusted house of Steris Healthcare

 

Benefits of Empagliflozin and Metformin ER Tablets

Superior Glycemic Control

Helps maintain HbA1c levels within target range

Weight Management

Promotes weight loss by increasing glucose excretion through urine

Heart Health

Reduces the risk of heart failure and other cardiovascular complications

Kidney Protection

Delays diabetic nephropathy progression and improves glomerular filtration rate (eGFR)

Lower Risk of Hypoglycemia

As it doesn’t stimulate insulin secretion, the risk of low blood sugar is minimal when used alone
 

Dosage and Administration

  • Standard Dosage: Typically 1 tablet once or twice daily based on the strength and patient profile
     
  • Mode of Intake: Should be taken with food to minimize gastrointestinal side effects
     
  • Available Combinations: Empagliflozin 10 mg/25 mg + Metformin ER 500 mg/1000 mg
     

Note: Always follow your doctor’s prescribed dosage and schedule for safe and effective use.

 

Possible Side Effects

Most side effects are mild and manageable, but some may require medical attention.

Common Side Effects:

  • Nausea
     
  • Diarrhea
     
  • Headache
     
  • Increased urination
     
  • Genital fungal infections (especially in women)
     

Rare but Serious Side Effects:

  • Lactic Acidosis (associated with Metformin – very rare)
     
  • Ketoacidosis (even with normal glucose levels)
     
  • Dehydration and low blood pressure
     
  • Urinary tract infections
     

Seek medical help if you experience unusual fatigue, muscle pain, labored breathing, or dizziness.

 

Who Should Avoid This Medicine?

Gliempaflozin Met ER should not be used in patients with:

  • Severe renal impairment (eGFR < 30 ml/min/1.73 m²)
     
  • Type 1 Diabetes Mellitus
     
  • History of lactic acidosis
     
  • Allergy to Empagliflozin, Metformin, or formulation excipients
     
  • Pregnancy or breastfeeding (unless approved by a healthcare provider)
     
  • Unstable cardiovascular conditions or hypotension

 

Drug Interactions to Consider

Some drugs may reduce efficacy or increase risks:

  • Diuretics (may cause dehydration)
     
  • NSAIDs (affect kidney function)
     
  • Insulin or insulin secretagogues (may increase hypoglycemia risk)
     
  • ACE inhibitors / ARBs
     
  • Contrast agents (caution advised in imaging procedures)
     

Always inform your physician about any ongoing medications or supplements.

 

Storage Guidelines

  • Store below 30°C, away from moisture and direct light
     
  • Keep out of reach of children
     
  • Do not use after the expiry date mentioned on the pack

Empagliflozin and Metformin ER Tablets Price in India

The price of Gliempaflozin Met ER may vary based on dosage strength, pack size, and region. Steris Healthcare offers a cost-effective solution for patients and institutions looking for a quality product without compromising affordability.

For the latest prices, contact Steris Healthcare Pvt Ltd or your nearest authorized distributor.

 

Why Choose Steris Healthcare for Gliempaflozin Met ER?

Steris Healthcare Pvt. Ltd. is recognized for its innovation, integrity, and quality-driven approach in pharmaceuticals. Their Empagliflozin and Metformin Hydrochloride Extended Release Tablets are manufactured under WHO-GMP certified facilities, ensuring maximum efficacy and patient safety.

What sets Steris Healthcare apart:

  • Rigorous Quality Control
     
  • Scientific Formulation Standards
     
  • Affordable & Accessible Pricing
     
  • Reliable Product Availability
     
  • Excellent Customer Support for Physicians and Distributors
     

Steris Healthcare’s Gliempaflozin Met ER provides comprehensive care by addressing not just blood sugar levels but also the broader complications of Type 2 diabetes, including cardiovascular and renal outcomes. This makes it a smart and dependable choice for patients, doctors, and healthcare providers alike. 

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