DILTIAZONE CD 120 is a prescription cardiovascular medication containing Diltiazem Hydrochloride Extended Release 120 mg, widely used for the management of hypertension, angina pectoris, and certain cardiac arrhythmias. Diltiazem belongs to the calcium channel blocker (CCB) class, which works by relaxing the blood vessels, reducing cardiac workload, and improving blood flow to the heart.

Hypertension and cardiac disorders are major health concerns in India, contributing significantly to cardiovascular morbidity and mortality. DILTIAZONE CD 120 provides a reliable and effective solution for these conditions, ensuring consistent therapeutic effects through extended-release formulation, which allows once-daily dosing for better adherence.

Uses

DILTIAZONE CD 120 is prescribed for several cardiovascular conditions where blood pressure control and improved cardiac perfusion are essential:

1. Hypertension

The extended-release formulation helps maintain stable blood pressure throughout the day, reducing the risk of stroke, heart attack, and other hypertension-related complications.

2. Angina Pectoris

By dilating coronary arteries, Diltiazem improves oxygen supply to the heart muscle, reducing chest pain and preventing angina attacks.

3. Cardiac Arrhythmias

DILTIAZONE CD 120 can be used to manage certain supraventricular tachycardias, atrial fibrillation, or flutter, helping maintain a normal heart rhythm.

4. Combination Therapy

It may be prescribed alongside other antihypertensive or anti-anginal agents, such as beta-blockers or diuretics, for patients requiring multi-drug therapy to achieve optimal cardiovascular control.

5. Chronic Cardiac Care

DILTIAZONE CD 120 is suitable for long-term management of hypertension and angina, providing sustained symptom relief and cardiovascular protection.

Benefits

DILTIAZONE CD 120 offers multiple clinical and patient-centric benefits:

1. Extended-Release Formulation

The controlled-release design ensures gradual drug absorption, maintaining stable blood levels throughout the day and reducing the frequency of dosing.

2. Blood Pressure Control

By relaxing vascular smooth muscles, DILTIAZONE CD 120 lowers both systolic and diastolic blood pressure, preventing long-term cardiovascular complications.

3. Angina Relief

Diltiazem improves myocardial oxygen supply, reducing chest pain episodes and enhancing exercise tolerance, allowing patients to perform daily activities with minimal discomfort.

4. Heart Rhythm Regulation

The drug helps manage certain arrhythmias by slowing conduction through the atrioventricular node, ensuring a more regular heart rhythm and reducing palpitations.

5. Improved Quality of Life

Regular therapy with DILTIAZONE CD 120 helps reduce symptoms such as headache, fatigue, and chest discomfort, improving overall patient well-being.

6. Safe and Well-Tolerated

DILTIAZONE CD 120 is generally well tolerated, making it suitable for long-term use in patients with hypertension, angina, or mild cardiac rhythm disorders.

Dosage

The dosage of DILTIAZONE CD 120 should be individualized according to the patient’s condition, blood pressure levels, and response to therapy.

Recommended Dosage:

• Usual Adult Dose: One tablet (120 mg) once daily

• Route: Oral

• Administration: Take with water, preferably at the same time each day, with or without food

Important Dosage Considerations:

• Dose may be adjusted based on clinical response or if combined with other antihypertensive medications

• Patients with renal or hepatic impairment may require dose modification

• Regular monitoring of blood pressure, heart rate, and cardiac function is recommended for optimal safety and efficacy

Side Effects

DILTIAZONE CD 120 is generally well tolerated, but some patients may experience side effects:

Common Side Effects:

• Headache

• Dizziness or lightheadedness

• Flushing

• Mild gastrointestinal disturbances, such as nausea or constipation

Less Common Side Effects:

• Slow heart rate (bradycardia)

• Swelling in the legs or ankles (peripheral edema)

• Fatigue or weakness

Rare but Serious Side Effects:

• Severe hypotension

• Worsening of heart failure in susceptible individuals

• Severe allergic reactions, including rash, swelling, or difficulty breathing

• Heart block or significant arrhythmias

Patients experiencing persistent, severe, or unusual side effects should contact their healthcare provider promptly.

Precautions and Warning

Certain precautions should be observed for safe and effective use of DILTIAZONE CD 120:

1. Blood Pressure and Heart Rate Monitoring

Patients with low blood pressure or pre-existing heart block should be closely monitored to avoid hypotension or bradycardia.

2. Kidney and Liver Function

Dose adjustments may be necessary in patients with renal or hepatic impairment to prevent accumulation and toxicity.

3. Pregnancy and Lactation

DILTIAZONE CD 120 should only be used during pregnancy or breastfeeding if clearly indicated and under medical supervision.

4. Drug Interactions

Inform your healthcare provider if taking:

• Beta-blockers or other antihypertensive agents

• Digoxin or anti-arrhythmic drugs

• CYP3A4 inhibitors or inducers, which may affect diltiazem metabolism

5. Lifestyle Measures

Optimal blood pressure control and angina management are achieved with balanced diet, regular exercise, weight management, smoking cessation, and stress reduction.

Conclusion

DILTIAZONE CD 120, containing Diltiazem Hydrochloride Extended Release 120 mg, is a clinically proven, safe, and effective therapy for managing hypertension, angina, and certain cardiac arrhythmias. Its extended-release formulation ensures sustained therapeutic effects, providing stable blood pressure control, improved coronary blood flow, and better heart rhythm management.

The medication’s oral once-daily dosing enhances patient adherence and convenience, while its favorable safety profile makes it suitable for long-term cardiovascular care. DILTIAZONE CD 120 is particularly beneficial for patients requiring continuous management of blood pressure, angina symptoms, or mild arrhythmias, offering a reliable solution for improved cardiovascular health and quality of life.