Introduction

DANOZOLIS 100 is a pharmaceutical formulation containing Danazol (100mg), a synthetic androgen derived from ethisterone. It is primarily used in the treatment of endometriosis, fibrocystic breast disease, and hereditary angioedema. This medication exerts its effects by modulating hormonal activity, leading to the suppression of ovulation and the reduction of estrogen production.

Key Ingredients

The active component in DANOZOLIS 100 is Danazol (100mg), a synthetic steroid with multiple physiological effects. It interacts with androgen and progesterone receptors, influencing various endocrine functions.

Uses of DANOZOLIS 100

1. Endometriosis Treatment

Danazol (100mg) is widely prescribed for endometriosis, a condition where endometrial tissue grows outside the uterus, causing pelvic pain and menstrual irregularities. By suppressing ovulation and lowering estrogen levels, DANOZOLIS 100 helps reduce endometrial tissue growth.

2. Fibrocystic Breast Disease

This medication is effective in alleviating symptoms of fibrocystic breast disease, a condition characterized by painful breast lumps. Danazol (100mg) works by altering hormone levels to reduce the formation of cysts and alleviate discomfort.

3. Hereditary Angioedema (HAE)

Patients with hereditary angioedema experience episodes of severe swelling in various body parts due to a deficiency of C1 inhibitor protein. DANOZOLIS 100 increases C1 inhibitor levels, preventing these painful and potentially dangerous attacks.

Mechanism of Action

Danazol (100mg) works by inhibiting the release of gonadotropins from the pituitary gland, leading to a reduction in luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels. This action suppresses ovarian function, decreasing estrogen production and alleviating symptoms of hormone-dependent conditions.

Dosage and Administration

• The usual dosage varies based on the condition being treated.

• For Endometriosis: The recommended dose is 200–800 mg per day, divided into two doses. DANOZOLIS 100 may be taken twice or thrice daily.

• For Fibrocystic Breast Disease: The standard dosage is 100–400 mg per day.

• For Hereditary Angioedema: Dosage typically ranges from 200 to 600 mg per day, adjusted according to the severity of symptoms.

• DANOZOLIS 100 should be taken with or without food, but maintaining a consistent schedule is essential for optimal efficacy.

Potential Side Effects

While DANOZOLIS 100 is effective, it may cause certain side effects, including:

• Weight gain

• Acne and oily skin

• Menstrual irregularities

• Mood changes and depression

• Deepening of the voice

• Hair growth (hirsutism)

• Liver enzyme abnormalities

• Hot flashes and sweating

Patients experiencing severe side effects should seek medical attention immediately.

Contraindications and Precautions

Contraindications:

• Pregnancy and breastfeeding – Danazol (100mg) can harm fetal development.

• Severe liver or kidney disease

• Uncontrolled heart disease

• Androgen-sensitive tumors (e.g., prostate cancer)

Precautions:

• Routine liver function tests are recommended during prolonged treatment.

• Women should use non-hormonal contraception while on DANOZOLIS 100.

• Patients with a history of migraine, epilepsy, or hypertension should use this medication cautiously.

Drug Interactions

DANOZOLIS 100 may interact with various medications, including:

• Warfarin – Increased risk of bleeding.

• Insulin and diabetes medications – May alter glucose metabolism.

• Corticosteroids – Potential for increased side effects.

• Cyclosporine and tacrolimus – Elevated toxicity risk.

Storage Instructions

• Store DANOZOLIS 100 in a cool, dry place, away from direct sunlight.

• Keep the medication out of reach of children.

• Do not use expired products.

Price in India

The price of DANOZOLIS 100 varies based on location and pharmacy. On average, a strip of 10 tablets may range from ₹200 to ₹500. It is advisable to check with local pharmacies for the latest pricing and availability.

Conclusion

DANOZOLIS 100, containing Danazol (100mg), is a potent medication for managing endometriosis, fibrocystic breast disease, and hereditary angioedema. While it offers significant benefits, it is essential to use it under medical supervision due to potential side effects and contraindications. Always consult a healthcare provider before starting or adjusting the dosage of DANOZOLIS 100.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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