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Alendronic Acid 35 mg Tablet: Uses, Dosage, Side Effects & Precautions

Sep 04, 2025

Introduction

Osteoporosis is a common condition characterized by weak and brittle bones, increasing the risk of fractures. ALENDROS 35 (Alendronic Acid 35 mg) is a bisphosphonate medication widely prescribed for prevention and treatment of osteoporosis in postmenopausal women and men at risk of fractures.While highly effective, some patients have reported side effects that can impact quality of life. Understanding the correct usage, precautions, and potential risks is essential for safe and effective treatment.

Composition

Each ALENDROS 35 tablet contains:

  • Alendronic Acid – 35 mg

Excipients: Microcrystalline cellulose, magnesium stearate, and other pharmaceutical-grade stabilizers for optimal bioavailability.

Mechanism of Action

Alendronic acid belongs to the bisphosphonate class, which works by:

  1. Inhibiting bone resorption – reduces the activity of osteoclasts (cells that break down bone).

  2. Increasing bone density – helps maintain stronger bones and reduces the risk of fractures.

  3. Maintaining skeletal integrity – preserves structural strength, especially in the spine and hip.

Uses of ALENDROS 35

  • Postmenopausal osteoporosis – to prevent fractures

  • Osteoporosis in men – reduces risk of fractures

  • Glucocorticoid-induced osteoporosis – protects bones during long-term steroid therapy

  • Paget’s disease of bone – sometimes prescribed to control abnormal bone remodeling

Dosage & Administration

  • Standard Dose: 35 mg once weekly

  • Administration: Take on an empty stomach with a full glass of water, at least 30 minutes before the first food, drink, or other medication of the day.

  • Position: Remain upright for at least 30 minutes after taking the tablet to prevent irritation of the esophagus.

  • Duration: As prescribed by the physician, usually long-term therapy for osteoporosis.

Important: Consistency in dosing and adherence to instructions is crucial for preventing fractures and bone loss.

Side Effects of Alendronic Acid

While effective, some patients report side effects that can significantly affect daily life:

Common Side Effects:

  • Heartburn, acid reflux

  • Nausea, abdominal pain

  • Diarrhea or constipation

  • Muscle or joint pain

Serious Side Effects (Rare):

  • Esophageal ulcers or irritation

  • Severe bone, joint, or muscle pain

  • Osteonecrosis of the jaw (especially after dental procedures)

  • Hypocalcemia (low calcium levels)

Patient Reports: Some patients have shared that long-term use has significantly impacted their quality of life, highlighting the importance of monitoring, correct usage, and regular consultation with healthcare providers.

Precautions & Warnings

  • Esophageal problems: Do not use if you have difficulty swallowing, esophageal stricture, or reflux.

  • Kidney disease: Use with caution; dosage adjustment may be needed.

  • Calcium and Vitamin D: Ensure adequate intake to support bone health.

  • Pregnancy & Lactation: Only under medical supervision.

  • Dental procedures: Inform your dentist before surgery due to rare risk of jaw osteonecrosis.

Drug Interactions

  • Calcium, antacids, iron supplements: Take these at least 30–60 minutes apart from ALENDROS 35.

  • Other bisphosphonates: Avoid combination therapy unless advised.

  • NSAIDs: May increase risk of gastrointestinal irritation.

Why Choose ALENDROS 35 from Steris Healthcare Pvt Ltd?

  • WHO-GMP certified – ensures high-quality and safe manufacturing

  • Clinically tested and reliable formulation

  • Affordable pricing and wide availability across India

  • Ethical and patient-centric services

By choosing Steris Healthcare, patients can ensure safe and effective therapy for osteoporosis with professional support.

FAQs (Frequently Asked Questions)

Q1. What is ALENDROS 35 used for?
It is used for the treatment and prevention of osteoporosis and bone fractures.

Q2. How should I take ALENDROS 35?
Take once weekly on an empty stomach with water, remain upright for 30 minutes, and avoid food or other medicines during this time.

Q3. Can ALENDROS 35 cause serious side effects?
Rarely, it may cause esophageal irritation, severe bone pain, or jaw osteonecrosis. Regular monitoring is recommended.

Q4. Can I stop taking ALENDROS 35 if I feel side effects?
Do not stop without consulting your doctor. Dose adjustment or alternative therapy may be suggested.

Q5. How long does it take to see results?
Bone density improvement is usually seen after 6–12 months; fracture risk reduction may take longer.

Q6. Can I take calcium and vitamin D supplements with this medicine?
Yes, but take them separately from ALENDROS 35, preferably 30–60 minutes apart.

Q7. Is ALENDROS 35 safe for elderly patients?
Yes, but they should take precautions regarding esophageal irritation and adequate hydration.

Conclusion

ALENDROS 35 (Alendronic Acid 35 mg) is a clinically proven therapy for osteoporosis, helping prevent fractures and improve bone health. While highly effective, patients should be aware of possible side effects and precautions, especially for long-term therapy.

ALENDROS 35 – Strengthen Your Bones, Reduce Fracture Risk, and Support a Healthier Life.

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